Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STM1131Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC77267.1); Blastp hit to AAC77267.1 (241 aa), 26% identity in aa 4 - 239. (230 aa)    
Predicted Functional Partners:
nanM
Putative inner membrane protein; Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta- anomer, accelerating the equilibrium between the alpha- and beta- anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses; Belongs to the NanM family.
  
  
 0.945
STM1132
Similar to E. coli putative transport protein (AAC77235.1); Blastp hit to AAC77235.1 (425 aa), 57% identity in aa 25 - 418.
  
  
 0.922
STM1760
Putative TPR repeat protein; Similar to E. coli orf, hypothetical protein (AAC73745.1); Blastp hit to AAC73745.1 (327 aa), 31% identity in aa 16 - 305, 33% identity in aa 29 - 273, 32% identity in aa 19 - 307, 33% identity in aa 47 - 320, 30-1073758628dentity in aa 22 - 312, 29% identity in aa 15 - 312, 34-1073758654dentity in aa 12 - 166.
   
  
 0.865
STM1127
Putative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC75480.1); Blastp hit to AAC75480.1 (285 aa), 29% identity in aa 15 - 264.
      
 0.853
STM1133
Putative dehydrogenases and related proteins; Similar to E. coli putative dehydrogenase (AAC77236.1); Blastp hit to AAC77236.1 (377 aa), 62% identity in aa 6 - 371.
  
  
 0.850
STM0295
Putative cytoplasmic protein.
   
  
 0.732
yhcO
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76271.1); Blastp hit to AAC76271.1 (90 aa), 76% identity in aa 1 - 90.
   
  
 0.732
STM1268
Putative cytoplasmic protein.
   
  
 0.728
STM0971
Putative cytoplasmic protein.
      
 0.726
STM1575
Putative transcriptional regulator, TetR family.
      
 0.726
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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