node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceA | aceB | STM4184 | STM4183 | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | Similar to E. coli malate synthase A (AAC76984.1); Blastp hit to AAC76984.1 (533 aa), 90% identity in aa 1 - 533. | 0.999 |
aceA | eda | STM4184 | STM1884 | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | Multifunctional; similar to E. coli 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase (AAC74920.1); Blastp hit to AAC74920.1 (213 aa), 97% identity in aa 1 - 212; oxaloacetate decarboxylase. | 0.935 |
aceA | ycdW | STM4184 | STM1135 | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | 0.912 |
aceA | yiaE | STM4184 | STM3646 | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | 2-keto-D-gluconate reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 0.911 |
aceB | aceA | STM4183 | STM4184 | Similar to E. coli malate synthase A (AAC76984.1); Blastp hit to AAC76984.1 (533 aa), 90% identity in aa 1 - 533. | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | 0.999 |
aceB | eda | STM4183 | STM1884 | Similar to E. coli malate synthase A (AAC76984.1); Blastp hit to AAC76984.1 (533 aa), 90% identity in aa 1 - 533. | Multifunctional; similar to E. coli 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase (AAC74920.1); Blastp hit to AAC74920.1 (213 aa), 97% identity in aa 1 - 212; oxaloacetate decarboxylase. | 0.929 |
aceB | ycdW | STM4183 | STM1135 | Similar to E. coli malate synthase A (AAC76984.1); Blastp hit to AAC76984.1 (533 aa), 90% identity in aa 1 - 533. | Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | 0.909 |
aceB | yiaE | STM4183 | STM3646 | Similar to E. coli malate synthase A (AAC76984.1); Blastp hit to AAC76984.1 (533 aa), 90% identity in aa 1 - 533. | 2-keto-D-gluconate reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 0.918 |
eda | aceA | STM1884 | STM4184 | Multifunctional; similar to E. coli 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase (AAC74920.1); Blastp hit to AAC74920.1 (213 aa), 97% identity in aa 1 - 212; oxaloacetate decarboxylase. | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | 0.935 |
eda | aceB | STM1884 | STM4183 | Multifunctional; similar to E. coli 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase (AAC74920.1); Blastp hit to AAC74920.1 (213 aa), 97% identity in aa 1 - 212; oxaloacetate decarboxylase. | Similar to E. coli malate synthase A (AAC76984.1); Blastp hit to AAC76984.1 (533 aa), 90% identity in aa 1 - 533. | 0.929 |
eda | ycdW | STM1884 | STM1135 | Multifunctional; similar to E. coli 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase (AAC74920.1); Blastp hit to AAC74920.1 (213 aa), 97% identity in aa 1 - 212; oxaloacetate decarboxylase. | Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | 0.905 |
eda | yiaE | STM1884 | STM3646 | Multifunctional; similar to E. coli 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase (AAC74920.1); Blastp hit to AAC74920.1 (213 aa), 97% identity in aa 1 - 212; oxaloacetate decarboxylase. | 2-keto-D-gluconate reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 0.906 |
gip | glxR | STM0518 | STM0519 | Similar to E. coli glyoxylate-induced protein (AAC73610.1); Blastp hit to AAC73610.1 (258 aa), 84% identity in aa 1 - 258; Belongs to the hyi family. | Tartronic semialdehyde reductase; Similar to E. coli putative oxidoreductase (AAC73611.1); Blastp hit to AAC73611.1 (292 aa), 91% identity in aa 1 - 292. | 0.984 |
gip | ycdW | STM0518 | STM1135 | Similar to E. coli glyoxylate-induced protein (AAC73610.1); Blastp hit to AAC73610.1 (258 aa), 84% identity in aa 1 - 258; Belongs to the hyi family. | Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | 0.925 |
gip | yiaE | STM0518 | STM3646 | Similar to E. coli glyoxylate-induced protein (AAC73610.1); Blastp hit to AAC73610.1 (258 aa), 84% identity in aa 1 - 258; Belongs to the hyi family. | 2-keto-D-gluconate reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 0.905 |
gloA | ycdW | STM1435 | STM1135 | Glyoxalase I; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | 0.902 |
gloA | yiaE | STM1435 | STM3646 | Glyoxalase I; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 2-keto-D-gluconate reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 0.908 |
glxR | gip | STM0519 | STM0518 | Tartronic semialdehyde reductase; Similar to E. coli putative oxidoreductase (AAC73611.1); Blastp hit to AAC73611.1 (292 aa), 91% identity in aa 1 - 292. | Similar to E. coli glyoxylate-induced protein (AAC73610.1); Blastp hit to AAC73610.1 (258 aa), 84% identity in aa 1 - 258; Belongs to the hyi family. | 0.984 |
glxR | ycdW | STM0519 | STM1135 | Tartronic semialdehyde reductase; Similar to E. coli putative oxidoreductase (AAC73611.1); Blastp hit to AAC73611.1 (292 aa), 91% identity in aa 1 - 292. | Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | 0.918 |
glxR | yiaE | STM0519 | STM3646 | Tartronic semialdehyde reductase; Similar to E. coli putative oxidoreductase (AAC73611.1); Blastp hit to AAC73611.1 (292 aa), 91% identity in aa 1 - 292. | 2-keto-D-gluconate reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 0.904 |