Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ycdYSimilar to E. coli putative oxidoreductase component (AAC74119.1); Blastp hit to AAC74119.1 (184 aa), 86% identity in aa 1 - 184. (184 aa)    
Predicted Functional Partners:
ycdX
Putative Histidinol phosphatase; Related to hydrolases of the PHP family; similar to E. coli orf, hypothetical protein (AAC74118.1); Blastp hit to AAC74118.1 (245 aa), 89% identity in aa 1 - 245.
 
 0.996
ycdW
Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
  
  
 0.935
ycdZ
Putative inner membrane protein; Hypothetical protein in phoH-csgG intergenic region. (SW:YCDZ_SALTY).
  
  
 0.926
yraM
Putative transglycosylase; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family.
  
    0.770
yhjJ
Putative Zn-dependent peptidase; Protein YHJJ precursor. (SW:YHJJ_SALTY); Belongs to the peptidase M16 family.
  
     0.766
trpR
Transcriptional repressor for trp operon and aroH; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity).
  
    0.762
wecF-2
Putative inner membrane protein; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family.
  
     0.761
ydbH
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74463.1); Blastp hit to AAC74463.1 (879 aa), 78% identity in aa 1 - 878.
  
    0.760
yhfK
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76383.1); Blastp hit to AAC76383.1 (696 aa), 86% identity in aa 1 - 695.
  
     0.760
yajG
Similar to E. coli putative polymerase/proteinase (AAC73537.1); Blastp hit to AAC73537.1 (226 aa), 85% identity in aa 20 - 226.
  
     0.752
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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