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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdoGPeriplasmic glucans biosynthesis protein; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (511 aa)    
Predicted Functional Partners:
mdoH
Membrane glycosyltransferase; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
  
 0.999
mdoC
Membrane protein; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
     
 0.910
yceK
Putative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC74134.1); Blastp hit to AAC74134.1 (75 aa), 86% identity in aa 1 - 75.
       0.610
yfgA
Putative membrane protein; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
  
  
 0.535
yrfF
Putative inner membrane protein; Involved in negative control of bacterial proliferation within fibroblasts; Belongs to the IgaA family.
      
 0.457
ymgE
Putative transglycosylase-associated protein; Similar to E. coli orf, hypothetical protein (AAC74279.1); Blastp hit to AAC74279.1 (84 aa), 91% identity in aa 1 - 83.
      
 0.450
rpsA
30S ribosomal subunit protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
   
    0.448
hcaT
Similar to E. coli MFS (major facilitator superfamily) transporter (AAC75589.1); Blastp hit to AAC75589.1 (379 aa), 88% identity in aa 1 - 376.
      
 0.419
rcsF
Regulator in colanic acid synthesis; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
   
  
 0.402
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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