Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yceHPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74151.1); Blastp hit to AAC74151.1 (215 aa), 86% identity in aa 1 - 215; Belongs to the UPF0502 family. (215 aa)    
Predicted Functional Partners:
mviM
Virulence factor MVIM. (SW:MVIM_SALTY); Belongs to the Gfo/Idh/MocA family.
 
    0.985
rimJ
Similar to E. coli acetylation of N-terminal alanine of 30S ribosomal subunit protein S5 (AAC74150.1); Blastp hit to AAC74150.1 (194 aa), 95% identity in aa 1 - 194.
 
  
 0.960
yjfJ
Putative phage shock protein A; IM30; suppresses sigma54-dependent transcription; similar to E. coli putative alpha helical protein (AAC77139.1); Blastp hit to AAC77139.1 (232 aa), 88% identity in aa 1 - 232.
  
   
 0.909
sppA
Protease IV; Signal peptide peptidase; similar to E. coli protease IV, a signal peptide peptidase (AAC74836.1); Blastp hit to AAC74836.1 (618 aa), 86% identity in aa 1 - 618.
      
 0.855
pspC
Phage shock protein; Regulatory gene; activates expression of psp operon with PspB; similar to E. coli phage shock protein: activates phage shock-protein expression (AAC74388.1); Blastp hit to AAC74388.1 (119 aa), 84% identity in aa 1 - 119.
      
 0.724
pspA
Phage shock protein; Negative regulatory gene for the psp opreon; similar to E. coli phage shock protein, inner membrane protein (AAC74386.1); Blastp hit to AAC74386.1 (222 aa), 91% identity in aa 1 - 222.
   
  
 0.581
yceL
Putative MFS superfamily transport protein; Similar to E. coli orf, hypothetical protein (AAC74149.1); Blastp hit to AAC74149.1 (412 aa), 92% identity in aa 11 - 412.
  
    0.465
mviN
Putative virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
       0.420
grxB
Glutaredoxin 2; Similar to E. coli glutaredoxin 2 (AAC74148.1); Blastp hit to AAC74148.1 (215 aa), 85% identity in aa 1 - 215.
  
    0.414
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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