Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
yceFPutative inhibitor of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (194 aa)    
Predicted Functional Partners:
yhgF
Putative RNase R; Similar to E. coli orf, hypothetical protein (AAC76432.1); Blastp hit to AAC76432.1 (740 aa), 94% identity in aa 1 - 740.
      
 0.899
yjgA
Similar to E. coli putative alpha helix protein (AAC77191.1); Blastp hit to AAC77191.1 (183 aa), 95% identity in aa 1 - 183; Belongs to the UPF0307 family.
      
 0.896
yhcC
Putative FeS oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC76243.1); Blastp hit to AAC76243.1 (309 aa), 94% identity in aa 1 - 307.
      
 0.812
yeeX
Similar to E. coli putative alpha helix protein (AAC75068.1); Blastp hit to AAC75068.1 (131 aa), 93% identity in aa 23 - 131; Belongs to the UPF0265 family.
   
  
 0.792
radC
Putative DNA repair protein; Associated with replication forks; similar to E. coli DNA repair protein (AAC76662.1); Blastp hit to AAC76662.1 (224 aa), 83% identity in aa 10 - 224; Belongs to the UPF0758 family. YicR subfamily.
 
  
 0.727
ybcJ
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73630.1); Blastp hit to AAC73630.1 (77 aa), 92% identity in aa 8 - 77.
      
 0.725
yggV
Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.700
yihA
Putative GTPase involved in coordination of cell cycle; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
  
  
 0.659
yhbY
Putative RNA-binding protein; Contains KH domain; similar to E. coli orf, hypothetical protein (AAC76212.1); Blastp hit to AAC76212.1 (97 aa), 95% identity in aa 1 - 97.
      
 0.649
ygjT
Putative resistance protein; Has been proposed to be a redox modulator. Belongs to the TerC family.
  
   
 0.637
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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