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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycfLPutative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC74188.1); Blastp hit to AAC74188.1 (125 aa), 80% identity in aa 1 - 125. (124 aa)    
Predicted Functional Partners:
ycfF
Putative protein kinase C inhibitor; Similar to E. coli orf, hypothetical protein (AAC74187.1); Blastp hit to AAC74187.1 (119 aa), 97% identity in aa 1 - 119.
  
  
 0.941
ychJ
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74315.1); Blastp hit to AAC74315.1 (152 aa), 78% identity in aa 1 - 152; Belongs to the UPF0225 family.
   
  
 0.939
ycfM
Putative outer membrane lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).
  
  
 0.932
ycfN
Putative cytoplasmic protein; Catalyzes the phosphorylation of thiamine to thiamine phosphate.
  
  
 0.816
nagZ
Putative glycosyl hydrolase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Plays a role in beta-lactam antibiotic resistance via its role in generating anhydro-N-acetylmuramic acid-linked peptides; these peptides function as signaling molecules that induce high-level expression of the beta-lactamase AmpC; Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
  
  
 0.801
ycfP
Putative esterase; Similar to E. coli orf, hypothetical protein (AAC74192.1); Blastp hit to AAC74192.1 (199 aa), 94% identity in aa 20 - 199; Belongs to the UPF0227 family.
     
 0.800
sppA
Protease IV; Signal peptide peptidase; similar to E. coli protease IV, a signal peptide peptidase (AAC74836.1); Blastp hit to AAC74836.1 (618 aa), 86% identity in aa 1 - 618.
      
 0.720
ybbN
Similar to E. coli putative thioredoxin-like protein (AAC73594.1); Blastp hit to AAC73594.1 (296 aa), 94% identity in aa 13 - 296.
      
 0.716
ydeD
Putative permease, integral membrane protein; May be an export pump for several amino acids and their metabolites, including cysteine; Belongs to the EamA transporter family.
      
 0.700
STM3167
Putative diadenosine tetraphosphate (Ap4A) hydrolase.
  
  
 0.602
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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