Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ycfJPutative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC74194.1); Blastp hit to AAC74194.1 (179 aa), 94% identity in aa 1 - 178. (179 aa)    
Predicted Functional Partners:
ypfG
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75519.1); Blastp hit to AAC75519.1 (347 aa), 77% identity in aa 1 - 347.
   
  
 0.866
ygaC
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75718.1); Blastp hit to AAC75718.1 (114 aa), 88% identity in aa 1 - 112.
   
  
 0.781
hslJ
Similar to E. coli heat shock protein hslJ (AAC74461.1); Blastp hit to AAC74461.1 (140 aa), 69% identity in aa 1 - 138.
   
  
 0.744
rseA
Anti sigma E (sigma 24) factor, negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytop [...]
  
    0.737
yhdV
Putative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC76299.1); Blastp hit to AAC76299.1 (73 aa), 98% identity in aa 1 - 73.
      
 0.726
ydiM
Similar to E. coli putative transport system permease protein (AAC74760.1); Blastp hit to AAC74760.1 (404 aa), 79% identity in aa 1 - 395.
      
 0.721
yjcB
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77030.1); Blastp hit to AAC77030.1 (116 aa), 83% identity in aa 24 - 116.
      
 0.719
yfcJ
Similar to E. coli putative transport protein (AAC75382.1); Blastp hit to AAC75382.1 (392 aa), 88% identity in aa 1 - 392.
      
 0.718
yfaO
Putative NTP pyrophosphohydrolases including oxidative damage repair enzymes; Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP); Belongs to the Nudix hydrolase family. NudI subfamily.
      
 0.675
yejG
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75242.1); Blastp hit to AAC75242.1 (114 aa), 90% identity in aa 1 - 114.
      
 0.644
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.