STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycfJPutative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC74194.1); Blastp hit to AAC74194.1 (179 aa), 94% identity in aa 1 - 178. (179 aa)    
Predicted Functional Partners:
ypfG
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75519.1); Blastp hit to AAC75519.1 (347 aa), 77% identity in aa 1 - 347.
   
  
 0.907
ygaC
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75718.1); Blastp hit to AAC75718.1 (114 aa), 88% identity in aa 1 - 112.
   
  
 0.844
yfaO
Putative NTP pyrophosphohydrolases including oxidative damage repair enzymes; Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP); Belongs to the Nudix hydrolase family. NudI subfamily.
      
 0.761
STM1513
Putative cytoplasmic protein; Hypothetical protein (gi|6851081).
   
  
 0.697
rseA
Anti sigma E (sigma 24) factor, negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytop [...]
  
    0.680
hslJ
Similar to E. coli heat shock protein hslJ (AAC74461.1); Blastp hit to AAC74461.1 (140 aa), 69% identity in aa 1 - 138.
   
  
 0.596
yjbE
Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC76996.1); Blastp hit to AAC76996.1 (80 aa), 96% identity in aa 1 - 80.
      
 0.579
yeeA
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75069.1); Blastp hit to AAC75069.1 (352 aa), 79% identity in aa 1 - 352.
  
     0.506
yraM
Putative transglycosylase; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family.
  
     0.499
csiE
Stationary phase inducible protein; Similar to E. coli orf, hypothetical protein (AAC75588.1); Blastp hit to AAC75588.1 (433 aa), 71% identity in aa 8 - 432.
  
     0.497
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.