Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ycfQPutative transcriptional repressor (TetR/AcrR family); Similar to E. coli orf, hypothetical protein (AAC74195.1); Blastp hit to AAC74195.1 (236 aa), 80% identity in aa 27 - 236. (211 aa)    
Predicted Functional Partners:
yjdC
Putative merR family bacterial regulatory protein; Similar to E. coli orf, hypothetical protein (AAC77095.1); Blastp hit to AAC77095.1 (199 aa), 88% identity in aa 9 - 199.
  
  
 0.787
ycfR
Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC74196.1); Blastp hit to AAC74196.1 (85 aa), 91% identity in aa 1 - 85.
  
  
 0.717
nemA
Similar to E. coli N-ethylmaleimide reductase (AAC74722.1); Blastp hit to AAC74722.1 (365 aa), 92% identity in aa 1 - 365.
  
  
 0.629
yacG
Putative cytoplasmic protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
      
 0.476
STM2275
Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74613.1); Blastp hit to AAC74613.1 (228 aa), 25% identity in aa 13 - 217.
      
 0.474
STM0563
Putative transcriptional regulator (AraC/XylS family); Similar to E. coli putative ARAC-type regulatory protein (AAC73408.1); Blastp hit to AAC73408.1 (284 aa), 71% identity in aa 1 - 282.
  
    0.432
STM2804
Putative cytoplasmic protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
    0.416
yjiE
Similar to E. coli putative transcriptional regulator LYSR-type (AAC77283.1); Blastp hit to AAC77283.1 (303 aa), 81% identity in aa 1 - 302; Belongs to the LysR transcriptional regulatory family.
  
 
 
 0.416
barA
Sensory histidine kinase; Similar to E. coli sensor-regulator, activates OmpR by phophorylation (AAC75828.1); Blastp hit to AAC75828.1 (918 aa), 90% identity in aa 1 - 918.
  
 
 
 0.410
yqhC
Putative AraC/XylS family transcriptional regulator; Similar to E. coli putative ARAC-type regulatory protein (AAC76046.1); Blastp hit to AAC76046.1 (375 aa), 83% identity in aa 72 - 375.
  
     0.407
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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