Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
potCSpermidine/putrescine transporter; ABC superfamily (membrane); similar to E. coli spermidine/putrescine transport system permease (AAC74208.1); Blastp hit to AAC74208.1 (264 aa), 96% identity in aa 1 - 258. (259 aa)    
Predicted Functional Partners:
potD
Spermidine/putrescine transporter; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine. Polyamine binding protein; Belongs to the bacterial solute-binding protein PotD/PotF family.
 0.999
potB
Spermidine/putrescine transporter; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
0.999
potA
Spermidine/putrescine transporter; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
 
 0.999
potH
Putrescine transporter; ABC superfamily (membrane); similar to E. coli putrescine transport protein; permease (AAC73943.1); Blastp hit to AAC73943.1 (317 aa), 92% identity in aa 1 - 317.
 
 0.997
potF
ABC superfamily (peri_perm), putrescine transporter; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.
 
 0.996
potG
Putrescine transporter; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
 
 
 0.994
phnT
2-aminoethylphosphonate transporter ATPase component; Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for energy coupling to the transport system.
 
 
 0.893
yabJ
Putative ABC-transport protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system (Probable). Is also involved in thiamine pyrophosphate (TPP) transport. Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
  
   
 0.654
yecE
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74938.1); Blastp hit to AAC74938.1 (272 aa), 82% identity in aa 1 - 272.
   
  
 0.616
sifA
Lysosomal glycoprotein (lgp)-containing structures; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is required for endosomal tubulation and formation of Salmonella-induced filaments (Sifs), which are filamentous structures containing lysosomal membrane glycoproteins within epithelial cells. Sif formation is concomitant with intracellular bacterial replication.
  
  
 0.597
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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