Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
envFPutative envelope lipoprotein; Probable lipoprotein ENVF precursor (SW:ENVF_SALTY). (262 aa)    
Predicted Functional Partners:
envE
Putative envelope protein; Probable lipoprotein ENVE precursor. (SW:ENVE_SALTY).
   
  
 0.898
pagD
PhoP regulated; Putative function in virulence. Could be involved in promoting S.typhimurium survival within macrophages.
   
  
 0.896
msgA
Macrophage survival gene; Affects survival in macrophages.
   
  
 0.729
yiiQ
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76902.1); Blastp hit to AAC76902.1 (199 aa), 81% identity in aa 1 - 198.
   
  
 0.676
pagC
Reduced macrophage survival protein; Essential for full virulence and survival within macrophages; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. Ail family.
      
 0.675
STM1250
Putative cytoplasmic protein.
      
 0.591
STM1239
Putative cytoplasmic protein.
   
  
 0.548
STM0719
Similar to E. coli UDP-galactopyranose mutase (AAC75097.1); Blastp hit to AAC75097.1 (367 aa), 39% identity in aa 5 - 366.
   
  
 0.514
iagB
Invasion protein IAGB precursor. (SW:IAGB_SALTY); Belongs to the IagB/IpgF/P19 family.
      
 0.475
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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