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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM1252Putative cytoplasmic protein. (347 aa)    
Predicted Functional Partners:
STM3175
Putative bacterial regulatory helix-turn-helix protein; araC family; similar to E. coli orf, hypothetical protein (AAC76059.1); Blastp hit to AAC76059.1 (160 aa), 54% identity in aa 6 - 159.
   
  
 0.896
melA
Alpha-galactosidase. (SW:AGAL_SALTY); Belongs to the glycosyl hydrolase 4 family.
   
  
 0.890
yeiA
Putative dihydropyrimidine dehydrogenase; Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity).
   
  
 0.766
ygiN
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76065.1); Blastp hit to AAC76065.1 (104 aa), 90% identity in aa 1 - 104.
      
 0.716
mdaB
NADPH specific quinone oxidoreductase; Drug modulator; similar to E. coli modulator of drug activity B (AAC76064.1); Blastp hit to AAC76064.1 (193 aa), 92% identity in aa 1 - 192.
      
 0.658
STM1253
Putative inner membrane protein; Similar to E. coli putative cytochrome (AAC75040.1); Blastp hit to AAC75040.1 (186 aa), 67% identity in aa 11 - 183.
   
  
 0.643
yijP
Putative integral membrane protein; Catalyzes the addition of a phosphoethanolamine moiety to the outer membrane lipopolysaccharide core; Belongs to the phosphoethanolamine transferase family. EptC/CptA subfamily.
      
 0.612
yibD
Similar to E. coli putative regulator (AAC76639.1); Blastp hit to AAC76639.1 (344 aa), 80% identity in aa 1 - 343.
   
  
 0.586
nanH
Sialidase; Cleaves the terminal sialic acid (N-acetyl neuraminic acid) from carbohydrate chains in glycoproteins providing free sialic acid which can be used as carbon and energy sources. Sialidases have been suggested to be pathogenic factors in microbial infections.
 
   
 0.581
ygiW
Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC76060.1); Blastp hit to AAC76060.1 (130 aa), 89% identity in aa 1 - 130.
      
 0.459
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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