Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yeaSPutative transport protein; Exporter of leucine; Belongs to the Rht family. (212 aa)    
Predicted Functional Partners:
ytfF
Putative cationic amino acid transporter; Similar to E. coli putative transmembrane subunit (AAC77167.1); Blastp hit to AAC77167.1 (324 aa), 81% identity in aa 4 - 323.
      
 0.897
yadH
Putative transport protein; ABC superfamily (membrane); similar to E. coli orf, hypothetical protein (AAC73239.1); Blastp hit to AAC73239.1 (256 aa), 94% identity in aa 1 - 256.
      
 0.896
yddG
Putative permease; Similar to E. coli orf, hypothetical protein (AAD13437.1); Blastp hit to AAD13437.1 (293 aa), 85% identity in aa 20 - 292.
      
 0.790
yggA
Putative LYSE family amino acid transport protein; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine (By similarity); Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
  
   
 0.728
ybbB
Putative ATPase; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain (Probable); Belongs to the SelU family.
      
 0.682
proY
Putative APC family, proline transporter; Permease that is involved in the transport across the cytoplasmic membrane of proline; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
      
 0.675
STM4011
Putative inner membrane protein.
  
     0.596
livM
High-affinity branched-chain amino acid transporter; Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane; Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily.
      
 0.580
STM4013
Putative membrane-associated metal-dependent hydrolase.
  
     0.580
STM4015
Putative cytoplasmic protein.
  
     0.548
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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