Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
STM1273Putative nitric oxide reductase. (213 aa)    
Predicted Functional Partners:
ybdN
Putative 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; Similar to E. coli orf, hypothetical protein (AAC73703.1); Blastp hit to AAC73703.1 (406 aa), 82% identity in aa 1 - 406.
      
 0.720
yejG
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75242.1); Blastp hit to AAC75242.1 (114 aa), 90% identity in aa 1 - 114.
   
  
 0.719
acnB
Aconitate hydratase 2; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and the 2- methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Also catalyzes the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnB functions as a RNA- binding regulatory protein which regulates FliC synthesis via interaction with the ftsH transcript to decrease the intracellular levels of FtsH. The lower levels of Fts [...]
      
 0.673
yrbF
Putative ABC superfamily transport protein; Atp_bind; similar to E. coli putative ATP-binding component of a transport system (AAC76227.1); Blastp hit to AAC76227.1 (269 aa), 94% identity in aa 1 - 266.
      
 0.642
lasT
Putative tRNA/tRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
      
 0.580
flgJ
Flagellar biosynthesis protein; Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
      
 0.547
ybdO
Similar to E. coli putative transcriptional regulator LYSR-type (AAC73704.1); Blastp hit to AAC73704.1 (300 aa), 54% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family.
   
  
 0.455
yjgD
Putative cytoplasmic protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
      
 0.452
yeaR
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74867.1); Blastp hit to AAC74867.1 (119 aa), 83% identity in aa 1 - 119.
       0.432
yoaG
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74866.1); Blastp hit to AAC74866.1 (60 aa), 96% identity in aa 1 - 60.
       0.432
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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