Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yeaQPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74865.1); Blastp hit to AAC74865.1 (82 aa), 95% identity in aa 1 - 82. (82 aa)    
Predicted Functional Partners:
napD
Periplasmic nitrate reductase; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
   
  
 0.725
yebG
DNA damage-inducible gene in SOS regulon, dependent on cyclic AMP and H-NS; Similar to E. coli orf, hypothetical protein (AAC74918.1); Blastp hit to AAC74918.1 (96 aa), 79% identity in aa 1 - 96.
      
 0.649
acrZ
Putative outer membrane or exported; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
   
  
 0.643
dinI
DNA damage-inducible protein I; Inhibits UmuD processing; similar to E. coli damage-inducible protein I (AAC74145.1); Blastp hit to AAC74145.1 (81 aa), 85% identity in aa 1 - 81.
      
 0.643
elaB
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75326.1); Blastp hit to AAC75326.1 (101 aa), 89% identity in aa 1 - 101.
  
  
 0.599
yiiU
Putative cytoplasmic protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
      
 0.560
osmE
Similar to E. coli activator of ntrL gene (AAC74809.1); Blastp hit to AAC74809.1 (112 aa), 96% identity in aa 1 - 112.
   
    0.559
ydiZ
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74794.1); Blastp hit to AAC74794.1 (96 aa), 69% identity in aa 1 - 94.
   
    0.525
ssaE
Secretion system effector; Putative secretory apparatus component (gi|3377860).
      
 0.513
ygaM
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75719.1); Blastp hit to AAC75719.1 (113 aa), 86% identity in aa 1 - 112.
  
  
 0.474
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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