Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yeaMSimilar to E. coli putative ARAC-type regulatory protein (AAC74860.1); Blastp hit to AAC74860.1 (273 aa), 76% identity in aa 5 - 256. (264 aa)    
Predicted Functional Partners:
yeaN
Similar to E. coli putative amino acid/amine transport protein (AAC74861.1); Blastp hit to AAC74861.1 (393 aa), 81% identity in aa 1 - 392.
 
  
 0.744
rhaS
Positive regulator for rhaBAD operon; Activates expression of the rhaBAD and rhaT operons.
   
 
 0.740
ybeR
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73746.1); Blastp hit to AAC73746.1 (235 aa), 62% identity in aa 1 - 235.
      
 0.723
eutR
Putative regulator ethanolamine operon; Activates the transcription of the eut operon. Also positively regulates its own transcription. Probably binds ethanolamine and vitamin B12 as effectors.
  
   
 0.682
yfjD
Similar to E. coli putative transport protein (AAC75662.1); Blastp hit to AAC75662.1 (227 aa), 94% identity in aa 1 - 227.
      
 0.672
yicL
Putative permease; Integral membrane protein; hypothetical protein in selC 3'region. (SW:YICL_SALTY).
      
 0.670
hiuH
Putative periplasmic or exported protein; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
      
 0.642
rhaR
Positive regulator for rhaRS operon; Activates expression of the rhaSR operon in response to L- rhamnose.
  
 
 0.611
ydcR
Putative gntR family regulatory protein; Similar to E. coli multi modular; putative transcriptional regulator; also putative ATP-binding component of a transport system (AAC74521.1); Blastp hit to AAC74521.1 (468 aa), 87% identity in aa 1 - 468.
  
  
 0.586
yfiF
Putative tRNA/rRNA methyltransferase; Similar to E. coli orf, hypothetical protein (AAC75634.1); Blastp hit to AAC75634.1 (345 aa), 87% identity in aa 1 - 345; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
      
 0.525
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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