Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yeaGPutative Ser protein kinase; Similar to E. coli orf, hypothetical protein (AAC74853.1); Blastp hit to AAC74853.1 (644 aa), 98% identity in aa 1 - 644. (644 aa)    
Predicted Functional Partners:
yeaH
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74854.1); Blastp hit to AAC74854.1 (427 aa), 94% identity in aa 1 - 423; Belongs to the UPF0229 family.
  
 0.999
ycgB
Similar to E. coli putative sporulation protein (AAC74272.1); Blastp hit to AAC74272.1 (510 aa), 96% identity in aa 1 - 510.
 
  
 0.999
yahO
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73432.1); Blastp hit to AAC73432.1 (91 aa), 72% identity in aa 1 - 91.
   
  
 0.837
yehY
Putative ABC-type proline/glycine betaine transport system, permease component; Similar to E. coli putative transport system permease protein (AAC75191.1); Blastp hit to AAC75191.1 (385 aa), 76% identity in aa 6 - 385.
   
  
 0.828
katE
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
  
 0.827
ygaM
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75719.1); Blastp hit to AAC75719.1 (113 aa), 86% identity in aa 1 - 112.
   
    0.818
otsA
Trehalose-6-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.
   
  
 0.776
poxB
Pyruvate dehydrogenase/oxidase FAD and thiamine PPi cofactors, cytoplasmic in absence of cofactors; Similar to E. coli pyruvate oxidase (AAC73958.1); Blastp hit to AAC73958.1 (572 aa), 94% identity in aa 1 - 572; Belongs to the TPP enzyme family.
   
  
 0.756
fbaB
3-oxoacyl-[acyl-carrier-protein] synthase I; Similar to E. coli orf, hypothetical protein (AAC75158.1); Blastp hit to AAC75158.1 (374 aa), 96% identity in aa 25 - 374.
   
    0.754
ydiZ
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74794.1); Blastp hit to AAC74794.1 (96 aa), 69% identity in aa 1 - 94.
   
    0.732
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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