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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yeaAHypothetical protein; Putative domain frequently associated with peptide methionine sulfoxide reductase; similar to E. coli orf, hypothetical protein (AAC74848.1); Blastp hit to AAC74848.1 (137 aa), 85% identity in aa 1 - 137. (147 aa)    
Predicted Functional Partners:
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.999
yeaC
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74847.1); Blastp hit to AAC74847.1 (105 aa), 87% identity in aa 16 - 105.
  
    0.968
msrP
Putative nitrate reductase; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal. The cata [...]
  
  
 0.890
yebR
Putative GAF domain-containing protein; Similar to E. coli orf, hypothetical protein (AAC74902.1); Blastp hit to AAC74902.1 (183 aa), 83% identity in aa 11 - 183.
  
  
 0.828
bisC
Similar to E. coli biotin sulfoxide reductase (AAC76575.1); Blastp hit to AAC76575.1 (739 aa), 86% identity in aa 2 - 739; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
      
 0.763
STM1078
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74051.1); Blastp hit to AAC74051.1 (164 aa), 91% identity in aa 27 - 164.
 
 
    0.715
STM0355
Putative copper chaperone.
   
  
 0.709
btuE
Vitamin B12 transport protein; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.
  
  
 0.691
gltA
Citrate synthase. (SW:CISY_SALTY).
   
    0.680
yfbU
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75354.1); Blastp hit to AAC75354.1 (170 aa), 95% identity in aa 7 - 170; Belongs to the UPF0304 family.
   
  
 0.670
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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