Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ydjAPutative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74835.1); Blastp hit to AAC74835.1 (183 aa), 88% identity in aa 1 - 183. (183 aa)    
Predicted Functional Partners:
yfcA
Similar to E. coli putative structural protein (AAC75387.1); Blastp hit to AAC75387.1 (269 aa), 90% identity in aa 1 - 269.
  
  
 0.924
gltS
GltS family glutamate transport protein; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
     
 0.900
STM2759
Putative dipeptide/oligopeptide/nickel ABC-type transport systems, periplasmic component; Similar to E. coli putative transport protein (AAC73180.1); Blastp hit to AAC73180.1 (551 aa), 27% identity in aa 19 - 545.
  
   
 0.874
lysR
Positive LysR family transcriptional regulator; Similar to E. coli positive regulator for lys (AAC75878.1); Blastp hit to AAC75878.1 (311 aa), 86% identity in aa 1 - 311; Belongs to the LysR transcriptional regulatory family.
      
 0.860
selD
Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP.
  
    0.721
rpsL
30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.
      
 0.678
yacC
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73233.1); Blastp hit to AAC73233.1 (156 aa), 95% identity in aa 42 - 156.
      
 0.676
ycaO
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73991.1); Blastp hit to AAC73991.1 (589 aa), 93% identity in aa 4 - 589.
 
  
 0.663
topB
DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
  
  
 0.659
yhiH
Putative ABC-type multidrug transport system; ATPase component; Permease component of an ABC-transporter; similar to E. coli putative ATP-binding component of a transport system, fragment 1 (AAC76511.1); Blastp hit to AAC76511.1 (894 aa), 89% identity in aa 1 - 894.
  
  
 0.594
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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