STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
osmESimilar to E. coli activator of ntrL gene (AAC74809.1); Blastp hit to AAC74809.1 (112 aa), 96% identity in aa 1 - 112. (113 aa)    
Predicted Functional Partners:
osmC
Putative resistance protein; Osmotically inducible; similar to E. coli osmotically inducible protein (AAC74555.1); Blastp hit to AAC74555.1 (143 aa), 92% identity in aa 1 - 143.
   
  
 0.921
ygaM
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75719.1); Blastp hit to AAC75719.1 (113 aa), 86% identity in aa 1 - 112.
   
    0.807
osmY
RpoS-dependent stationary phase gene; similar to E. coli hyperosmotically inducible periplasmic protein (AAC77329.1); Blastp hit to AAC77329.1 (201 aa), 89% identity in aa 1 - 201.
   
  
 0.787
ygaU
Putative LysM domain protein; Similar to E. coli orf, hypothetical protein (AAC75712.1); Blastp hit to AAC75712.1 (149 aa), 93% identity in aa 1 - 149.
   
  
 0.785
osmB
Osmotically inducible lipoprotein; Provides resistance to osmotic stress. May be important for stationary-phase survival (By similarity).
   
  
 0.770
rpoS
Sigma S (sigma 38) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
   
  
 0.699
elaB
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75326.1); Blastp hit to AAC75326.1 (101 aa), 89% identity in aa 1 - 101.
   
    0.698
osmX
Putative periplasmic component; Part of the OsmU ABC transporter complex, which is involved in the uptake of osmoprotectants such as choline-O-sulfate and glycine betaine.
   
  
 0.676
yaeT
Putative outer membrane antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
    
 
 0.668
yeaG
Putative Ser protein kinase; Similar to E. coli orf, hypothetical protein (AAC74853.1); Blastp hit to AAC74853.1 (644 aa), 98% identity in aa 1 - 644.
   
    0.647
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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