STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
celDAraC/XylS family; similar to E. coli negative transcriptional regulator of cel operon (AAC74805.1); Blastp hit to AAC74805.1 (280 aa), 85% identity in aa 1 - 280. (280 aa)    
Predicted Functional Partners:
celC
Similar to E. coli PEP-dependent phosphotransferase enzyme III for cellobiose, arbutin, and salicin (AAC74806.1); Blastp hit to AAC74806.1 (116 aa), 87% identity in aa 1 - 115.
  
 0.963
celB
PTS family sugar specific enzyme II for cellobiose, arbutin, and salicin; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
  
 0.962
celA
Similar to E. coli PEP-dependent phosphotransferase enzyme IV for cellobiose, arbutin, and salicin (AAC74808.1); Blastp hit to AAC74808.1 (106 aa), 96% identity in aa 1 - 106.
   
 0.920
celF
Similar to E. coli phospho-beta-glucosidase; cryptic (AAC74804.1); Blastp hit to AAC74804.1 (450 aa), 90% identity in aa 1 - 450; cellobiose-6-phosphate hydrolase.
  
 0.891
celG
Putative glucosidase; Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, t [...]
 
  
 0.809
leuO
Putative LysR family transcriptional regulator; Probable activator protein in leuabcd operon. (SW:LEUO_SALTY); Belongs to the LysR transcriptional regulatory family.
  
  
 0.738
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
      
 0.718
fucR
DeoR family; similar to E. coli positive regulator of the fuc operon (AAC75847.1); Blastp hit to AAC75847.1 (243 aa), 88% identity in aa 1 - 235.
      
 0.718
kbl
2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
     
 0.709
ilvN
Similar to E. coli acetolactate synthase I, valine sensitive, small subunit (AAC76693.1); Blastp hit to AAC76693.1 (96 aa), 90% identity in aa 1 - 96.
      
 0.700
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.