Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pfkBSimilar to E. coli 6-phosphofructokinase II; suppressor of pfkA (AAC74793.1); Blastp hit to AAC74793.1 (309 aa), 92% identity in aa 1 - 308; Belongs to the carbohydrate kinase PfkB family. (310 aa)    
Predicted Functional Partners:
fbaB
3-oxoacyl-[acyl-carrier-protein] synthase I; Similar to E. coli orf, hypothetical protein (AAC75158.1); Blastp hit to AAC75158.1 (374 aa), 96% identity in aa 25 - 374.
 
 
 0.988
pfkA
6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
   
 
 0.974
talA
Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
   
 
 0.971
fruA
Fructose-specific transport protein; Sugar Specific PTS system; similar to E. coli PTS system, fructose-specific transport protein (AAC75228.1); Blastp hit to AAC75228.1 (563 aa), 92% identity in aa 1 - 563.
  
 0.968
STM3255
Putative phosphotransferase system fructose-specific component IIB; Similar to E. coli PTS system, fructose-specific transport protein (AAC75228.1); Blastp hit to AAC75228.1 (563 aa), 42% identity in aa 104 - 562, 32% identity in aa 2 - 41.
 
  
 0.962
STM3858
Putative phosphotransferase system fructose-specific component IIB; Similar to E. coli PTS system, fructose-specific transport protein (AAC75228.1); Blastp hit to AAC75228.1 (563 aa), 66% identity in aa 104 - 552.
  
 0.958
fbp
Similar to E. coli fructose-bisphosphatase (AAC77189.1); Blastp hit to AAC77189.1 (332 aa), 97% identity in aa 1 - 332.
   
 
 0.946
tktB
Transketolase 2 isozyme; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 
 0.945
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.936
STM3251
Putative ribokinase family sugar kinase; Similar to E. coli ribokinase (AAC76775.1); Blastp hit to AAC76775.1 (309 aa), 23% identity in aa 6 - 308.
 
 
 0.935
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.