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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkBSimilar to E. coli 6-phosphofructokinase II; suppressor of pfkA (AAC74793.1); Blastp hit to AAC74793.1 (309 aa), 92% identity in aa 1 - 308; Belongs to the carbohydrate kinase PfkB family. (310 aa)    
Predicted Functional Partners:
fbaB
3-oxoacyl-[acyl-carrier-protein] synthase I; Similar to E. coli orf, hypothetical protein (AAC75158.1); Blastp hit to AAC75158.1 (374 aa), 96% identity in aa 25 - 374.
 
 
 0.990
fruA
Fructose-specific transport protein; Sugar Specific PTS system; similar to E. coli PTS system, fructose-specific transport protein (AAC75228.1); Blastp hit to AAC75228.1 (563 aa), 92% identity in aa 1 - 563.
  
 0.989
pfkA
6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
     
 0.981
talA
Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
   
 
 0.972
STM3255
Putative phosphotransferase system fructose-specific component IIB; Similar to E. coli PTS system, fructose-specific transport protein (AAC75228.1); Blastp hit to AAC75228.1 (563 aa), 42% identity in aa 104 - 562, 32% identity in aa 2 - 41.
  
 0.970
STM3858
Putative phosphotransferase system fructose-specific component IIB; Similar to E. coli PTS system, fructose-specific transport protein (AAC75228.1); Blastp hit to AAC75228.1 (563 aa), 66% identity in aa 104 - 552.
  
 0.965
ptsA
General PTS family enzyme I; Similar to E. coli PEP-protein phosphotransferase system enzyme I (AAC76929.1); Blastp hit to AAC76929.1 (711 aa), 90% identity in aa 1 - 711.
  
  
 0.959
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.953
tktB
Transketolase 2 isozyme; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 
 0.947
srlD
Similar to E. coli glucitol (sorbitol)-6-phosphate dehydrogenase (AAC75747.1); Blastp hit to AAC75747.1 (259 aa), 97% identity in aa 1 - 259; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
  0.939
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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