STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rfcO-antigen polymerase; May link the O-antigen tetrasaccharide units into long chains, giving rise to typical smooth LPS. (407 aa)    
Predicted Functional Partners:
STM1331
Putative inner membrane protein.
   
  
 0.897
wcaH
GDP-mannose mannosyl hydrolase; In colanic acid gene clustersimilar to E. coli GDP-mannose mannosyl hydrolase (AAC75112.1); Blastp hit to AAC75112.1 (160 aa), 78% identity in aa 15 - 149.
      
 0.769
rfaL
O-antigen ligase; Adds the O-antigen on the glucose(II) group of LPS.
   
  
 0.731
rfbJ
LPS side chain defect; CDP-abequose synthase. (SW:RFBJ_SALTY).
   
  
 0.677
rfbM
Mannose-1-phosphate guanylyltransferase; Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS group B O antigen; Belongs to the mannose-6-phosphate isomerase type 2 family.
   
  
 0.529
rfbK
Phosphomannomutase; Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS group B O antigen; Belongs to the phosphohexose mutase family.
   
  
 0.512
iap
Similar to E. coli alkaline phosphatase isozyme conversion, aminopeptidase (AAC75795.1); Blastp hit to AAC75795.1 (345 aa), 85% identity in aa 1 - 344.
      
 0.475
yedF
Putative transcriptional regulator; Hypothetical 8.6 Kda protein in amyA-fliE intergenic region (ORF 9). (SW:YEDF_ECOLI); Belongs to the sulfur carrier protein TusA family.
      
 0.463
ydiY
Putative salt-induced outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC74792.1); Blastp hit to AAC74792.1 (252 aa), 88% identity in aa 1 - 252.
      
 0.451
ydeI
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74609.1); Blastp hit to AAC74609.1 (130 aa), 79% identity in aa 1 - 130.
      
 0.405
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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