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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ydiOPutative acyl-CoA dehydrogenase; Similar to E. coli putative oxidoreductase (AAC74765.1); Blastp hit to AAC74765.1 (401 aa), 95% identity in aa 19 - 401. (383 aa)    
Predicted Functional Partners:
fadB
3-hydroxyacyl-coA dehydrogenase of 4-enzyme FadB protein; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
 
 0.992
ydiR
Similar to E. coli putative flavoprotein (AAC74768.1); Blastp hit to AAC74768.1 (312 aa), 72% identity in aa 1 - 312.
 
 0.987
yfcX
Putative dehydrogenase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.987
fixB
Putative electron transfer flavoprotein, carnitine metabolism; Required for anaerobic carnitine reduction. May bring reductant to CaiA.
 
 
 0.979
yqeF
Putative acetyl-CoA acetyltransferase; Similar to E. coli putative acyltransferase (AAC75883.1); Blastp hit to AAC75883.1 (394 aa), 91% identity in aa 2 - 393; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.972
STM0856
Putative electron transfer flavoprotein alpha subunit; Similar to E. coli putative flavoprotein (AAC74768.1); Blastp hit to AAC74768.1 (312 aa), 35% identity in aa 65 - 310.
 
 0.915
ydiF
Putative acetyl-CoA:acetoacetyl-CoA transferase beta subunit; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.
 
  
 0.908
caiD
Carnitine racemase; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA.
 
 0.896
ydiQ
Putative electron transfer flavoprotein; Similar to E. coli putative transport protein (AAC74767.1); Blastp hit to AAC74767.1 (254 aa), 79% identity in aa 1 - 254.
 
 
 0.879
fixA
Putative flavoprotein reductase, carnitine metabolism; Required for anaerobic carnitine reduction. May bring reductant to CaiA.
 
 
 
 0.857
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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