Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ydiNSimilar to E. coli putative amino acid/amine transport protein (AAC74761.1); Blastp hit to AAC74761.1 (423 aa), 85% identity in aa 3 - 412. (411 aa)    
Predicted Functional Partners:
ydiB
Putative shikimate 5-dehydrogenase; The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
 
  
 0.975
aroD
3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. The reaction involves the formation of an imine intermediate between the keto group of 3-dehydroquinate and the epsylon-amino group of a lys-170 at the active site. Belongs to the type-I 3-dehydroquinase family.
 
  
 0.912
STM1029
Gifsy-2 prophage protein; Bacteriophage ES18 gp15 protein (gi|1143595).
   
  
 0.897
STM1015
Gifsy-2 prophage ATPase involved in DNA replication initiation; dnaC protein homolog (gi|7443681).
      
 0.896
STM2239
Similar to antiterminator protein Q of phage P5; similar to E. coli orf, hypothetical protein (AAC73652.1); Blastp hit to AAC73652.1 (127 aa), 47% identity in aa 1 - 121.
      
 0.857
STM3631
Similar to E. coli putative permease (AAC75926.1); Blastp hit to AAC75926.1 (505 aa), 27% identity in aa 54 - 466.
      
 0.767
ybaN
Similar to E. coli putative gene 58 (AAC73570.1); Blastp hit to AAC73570.1 (125 aa), 84% identity in aa 1 - 124.
      
 0.723
STM2913
Similar to E. coli putative transport protein (AAC75782.1); Blastp hit to AAC75782.1 (454 aa), 33% identity in aa 11 - 446.
      
 0.722
ybaO
Similar to E. coli putative LRP-like transcriptional regulator (AAC73550.1); Blastp hit to AAC73550.1 (181 aa), 95% identity in aa 30 - 181.
      
 0.649
yejF
Contains duplicated ATPase domain; similar to E. coli putative ATP-binding component of a transport system (AAC75241.1); Blastp hit to AAC75241.1 (529 aa), 86% identity in aa 1 - 529; Belongs to the ABC transporter superfamily.
      
 0.617
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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