STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
orf48Amino acid permease YeeF like protein (gi|1526981). (447 aa)    
Predicted Functional Partners:
orf32
Putative hydrolase or acyltransferase; Proline iminopeptidase like protein (gi|1526980).
 
  
 0.985
ychA
Putative transcriptional regulator; Required for maximal expression of sirC, not required to invade host cells; Belongs to the UPF0162 family.
      
 0.799
STM3605
Putative phage endolysin.
      
 0.753
orf245
Putative cytoplasmic protein; ORF 245 (gi|4456875).
  
  
 0.747
sirC
Regulator of invasion genes; Required for maximal expression of sirC, not required to invade host cells.
      
 0.721
orf408
Putative regulatory protein, deoR family; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 
 0.665
ydaL
Putative Smr domain protein; Similar to E. coli orf, hypothetical protein (AAC74422.1); Blastp hit to AAC74422.1 (187 aa), 86% identity in aa 1 - 187.
   
  
 0.654
STM2357
Similar to E. coli putative amino acid/amine transport protein (AAC73363.1); Blastp hit to AAC73363.1 (475 aa), 36% identity in aa 9 - 463.
  
    0.581
ssb
ssDNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
      
 0.514
ssaU
Secretion system apparatus protein; Part of a type III secretion system; Belongs to the type III secretion exporter family.
   
  
 0.489
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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