STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
orf32Putative hydrolase or acyltransferase; Proline iminopeptidase like protein (gi|1526980). (297 aa)    
Predicted Functional Partners:
orf48
Amino acid permease YeeF like protein (gi|1526981).
 
  
 0.985
putA
Plasma membrane proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
     
 0.913
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
  0.901
STM4211
Putative phage tail protein.
      
 0.895
orf245
Putative cytoplasmic protein; ORF 245 (gi|4456875).
 
  
 0.781
sirC
Regulator of invasion genes; Required for maximal expression of sirC, not required to invade host cells.
      
 0.670
orf408
Putative regulatory protein, deoR family; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
  
 0.653
ychA
Putative transcriptional regulator; Required for maximal expression of sirC, not required to invade host cells; Belongs to the UPF0162 family.
      
 0.613
STM3605
Putative phage endolysin.
   
  
 0.547
yajD
Putative cytoplasmic protein; Hypothetical 12.6 Kda protein in secF-tsx intergenic region. (SW:YAJD_SALTY); Belongs to the HNH nuclease family.
      
 0.513
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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