Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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orf319Putative inner membrane protein; ORF 319 (gi|4456867). (319 aa)    
Predicted Functional Partners:
phrB
Deoxyribodipyrimidine photolyase (photoreactivation); Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation; Belongs to the DNA photolyase class-1 family.
  
  
 0.922
thiI
Sulfur transfer protein (from cys to ThiS and from IscS to U8-tRNA); Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
   
 0.771
orf242
Putative regulatory proteins, merR family; ORF 242 (gi|4456866).
  
  
 0.723
ygcH
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75798.1); Blastp hit to AAC75798.1 (199 aa), 28% identity in aa 3 - 198.
      
 0.649
yggR
Similar to E. coli putative protein transport (AAC75987.1); Blastp hit to AAC75987.1 (341 aa), 79% identity in aa 16 - 341.
      
 0.633
yjhP
Similar to E. coli putative methyltransferase (AAC77262.1); Blastp hit to AAC77262.1 (248 aa), 30% identity in aa 1 - 138.
  
  
 0.530
cfa
Similar to E. coli cyclopropane fatty acyl phospholipid synthase (AAC74733.1); Blastp hit to AAC74733.1 (382 aa), 90% identity in aa 1 - 382.
  
  
 0.509
STM1266
Similar to E. coli putative transcriptional regulator (AAC74246.1); Blastp hit to AAC74246.1 (243 aa), 31% identity in aa 1 - 241.
  
  
 0.499
yehV
Putative transcriptional repressor (MerR family); Transcriptional activator of csgD, which is required for production of the curli (AgF).
  
  
 0.499
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
  
  
 0.471
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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