Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ssaMSecretion system apparatus protein SSAM. (SW:SSAM_SALTY). (122 aa)    
Predicted Functional Partners:
ssaL
Secretion system apparatus protein SSAL. (SW:SSAL_SALTY).
  
  
 0.985
ssaP
Secretion system apparatus protein SSAP. (SW:SSAP_SALTY).
  
  
 0.956
ssaG
Secretion system apparatus; SsaH (gi|2460267).
  
  
 0.940
ssaR
Homology with YscR of the secretion system of Yersinia; virulence protein yscr (SW:YSCR_SALTY).
  
  
 0.934
ssaB
Secretion system apparatus protein; Virulence protein that plays a central role in mammalian macrophage infection, by inhibiting phagosome-lysosome fusion and cellular trafficking. May act by disrupting the function of the mammalian HOOK3 protein, a protein involved in the cellular traffic.
  
  
 0.925
ssaQ
Secretion system apparatus protein; Part of a type III secretion system.
  
  
 0.924
ssaO
Secretion system apparatus protein SSAO. (SW:SSAO_SALTY).
  
  
 0.887
ssaV
Secretion system apparatus protein; Component of Salmonella pathogenicity island 2 (SPI-2) type III secretion system, required for secretion of some type III-secreted effectors including the SpvB toxin.
  
  
 0.886
STM1410
Putative cytoplasmic protein.
  
  
 0.877
ssaJ
Secretion system apparatus protein; Component of Salmonella pathogenicity island 2 (SPI-2) type III secretion system, required for secretion of some type III-secreted effectors including the SpvB toxin.
  
  
 0.872
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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