Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cfaSimilar to E. coli cyclopropane fatty acyl phospholipid synthase (AAC74733.1); Blastp hit to AAC74733.1 (382 aa), 90% identity in aa 1 - 382. (382 aa)    
Predicted Functional Partners:
yhbT
Putative lipid carrier protein; Similar to E. coli orf, hypothetical protein (AAC76191.1); Blastp hit to AAC76191.1 (174 aa), 90% identity in aa 1 - 174.
      
 0.854
ydiU
Putative cytoplasmic protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
  
   
 0.729
pfkB
Similar to E. coli 6-phosphofructokinase II; suppressor of pfkA (AAC74793.1); Blastp hit to AAC74793.1 (309 aa), 92% identity in aa 1 - 308; Belongs to the carbohydrate kinase PfkB family.
   
    0.679
fbaB
3-oxoacyl-[acyl-carrier-protein] synthase I; Similar to E. coli orf, hypothetical protein (AAC75158.1); Blastp hit to AAC75158.1 (374 aa), 96% identity in aa 25 - 374.
   
  
 0.673
STM1634
Putative amino acid ABC transporter permease component; Similar to E. coli putative transport system permease protein (former yecC) (AAC74985.1); Blastp hit to AAC74985.1 (222 aa), 31% identity in aa 14 - 213.
      
 0.556
fabG
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
 
 
  
 0.531
orf319
Putative inner membrane protein; ORF 319 (gi|4456867).
  
  
 0.509
otsA
Trehalose-6-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.
  
    0.507
talA
Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
   
  
 0.507
wraB
Similar to E. coli trp repressor binding protein; affects association of trp repressor and operator (AAC74089.1); Blastp hit to AAC74089.1 (198 aa), 94% identity in aa 1 - 198.
   
  
 0.503
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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