Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nemASimilar to E. coli N-ethylmaleimide reductase (AAC74722.1); Blastp hit to AAC74722.1 (365 aa), 92% identity in aa 1 - 365. (365 aa)    
Predicted Functional Partners:
nfnB
Dihydropteridine reductase; Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone (By similarity).
 
 
 0.921
gloA
Glyoxalase I; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
  
 0.917
mdaA
Oxygen-insensitive NADPH nitroreductase; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product.
  
 
 0.908
ydhM
Putative TetR/AcrR family transcriptional repressor; Similar to E. coli orf, hypothetical protein (AAC74721.1); Blastp hit to AAC74721.1 (199 aa), 83% identity in aa 1 - 197.
 
  
 0.795
ycfQ
Putative transcriptional repressor (TetR/AcrR family); Similar to E. coli orf, hypothetical protein (AAC74195.1); Blastp hit to AAC74195.1 (236 aa), 80% identity in aa 27 - 236.
  
  
 0.629
tldD
Similar to E. coli suppresses inhibitory activity of CsrA (AAC76276.1); Blastp hit to AAC76276.1 (481 aa), 94% identity in aa 1 - 481.
      
 0.556
STM1674
Putative AraC family bacterial regulatory helix-turn-helix protein; Similar to E. coli orf, hypothetical protein (AAC77208.1); Blastp hit to AAC77208.1 (84 aa), 46% identity in aa 1 - 84.
  
  
 0.496
ydhF
Putative aldo/keto reductase; Similar to E. coli orf, hypothetical protein (AAC74719.1); Blastp hit to AAC74719.1 (298 aa), 89% identity in aa 1 - 298.
 
    0.471
yfcX
Putative dehydrogenase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 0.466
fadB
3-hydroxyacyl-coA dehydrogenase of 4-enzyme FadB protein; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
  
 0.466
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.