| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gloA | nemA | STM1435 | STM1436 | Glyoxalase I; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | Similar to E. coli N-ethylmaleimide reductase (AAC74722.1); Blastp hit to AAC74722.1 (365 aa), 92% identity in aa 1 - 365. | 0.917 |
| gloA | ydhL | STM1435 | STM1438 | Glyoxalase I; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74720.1); Blastp hit to AAC74720.1 (125 aa), 83% identity in aa 47 - 125. | 0.609 |
| gloA | ydhM | STM1435 | STM1437 | Glyoxalase I; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | Putative TetR/AcrR family transcriptional repressor; Similar to E. coli orf, hypothetical protein (AAC74721.1); Blastp hit to AAC74721.1 (199 aa), 83% identity in aa 1 - 197. | 0.625 |
| nemA | gloA | STM1436 | STM1435 | Similar to E. coli N-ethylmaleimide reductase (AAC74722.1); Blastp hit to AAC74722.1 (365 aa), 92% identity in aa 1 - 365. | Glyoxalase I; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.917 |
| nemA | ydhF | STM1436 | STM1439 | Similar to E. coli N-ethylmaleimide reductase (AAC74722.1); Blastp hit to AAC74722.1 (365 aa), 92% identity in aa 1 - 365. | Putative aldo/keto reductase; Similar to E. coli orf, hypothetical protein (AAC74719.1); Blastp hit to AAC74719.1 (298 aa), 89% identity in aa 1 - 298. | 0.471 |
| nemA | ydhL | STM1436 | STM1438 | Similar to E. coli N-ethylmaleimide reductase (AAC74722.1); Blastp hit to AAC74722.1 (365 aa), 92% identity in aa 1 - 365. | Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74720.1); Blastp hit to AAC74720.1 (125 aa), 83% identity in aa 47 - 125. | 0.452 |
| nemA | ydhM | STM1436 | STM1437 | Similar to E. coli N-ethylmaleimide reductase (AAC74722.1); Blastp hit to AAC74722.1 (365 aa), 92% identity in aa 1 - 365. | Putative TetR/AcrR family transcriptional repressor; Similar to E. coli orf, hypothetical protein (AAC74721.1); Blastp hit to AAC74721.1 (199 aa), 83% identity in aa 1 - 197. | 0.795 |
| ybjZ | ydhM | STM0942 | STM1437 | Putative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Putative TetR/AcrR family transcriptional repressor; Similar to E. coli orf, hypothetical protein (AAC74721.1); Blastp hit to AAC74721.1 (199 aa), 83% identity in aa 1 - 197. | 0.461 |
| ydcI | ydhM | STM1625 | STM1437 | Similar to E. coli putative transcriptional regulator LYSR-type (AAC74504.1); Blastp hit to AAC74504.1 (354 aa), 83% identity in aa 48 - 353; Belongs to the LysR transcriptional regulatory family. | Putative TetR/AcrR family transcriptional repressor; Similar to E. coli orf, hypothetical protein (AAC74721.1); Blastp hit to AAC74721.1 (199 aa), 83% identity in aa 1 - 197. | 0.586 |
| ydhF | nemA | STM1439 | STM1436 | Putative aldo/keto reductase; Similar to E. coli orf, hypothetical protein (AAC74719.1); Blastp hit to AAC74719.1 (298 aa), 89% identity in aa 1 - 298. | Similar to E. coli N-ethylmaleimide reductase (AAC74722.1); Blastp hit to AAC74722.1 (365 aa), 92% identity in aa 1 - 365. | 0.471 |
| ydhF | ydhL | STM1439 | STM1438 | Putative aldo/keto reductase; Similar to E. coli orf, hypothetical protein (AAC74719.1); Blastp hit to AAC74719.1 (298 aa), 89% identity in aa 1 - 298. | Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74720.1); Blastp hit to AAC74720.1 (125 aa), 83% identity in aa 47 - 125. | 0.645 |
| ydhF | ydhM | STM1439 | STM1437 | Putative aldo/keto reductase; Similar to E. coli orf, hypothetical protein (AAC74719.1); Blastp hit to AAC74719.1 (298 aa), 89% identity in aa 1 - 298. | Putative TetR/AcrR family transcriptional repressor; Similar to E. coli orf, hypothetical protein (AAC74721.1); Blastp hit to AAC74721.1 (199 aa), 83% identity in aa 1 - 197. | 0.465 |
| ydhL | gloA | STM1438 | STM1435 | Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74720.1); Blastp hit to AAC74720.1 (125 aa), 83% identity in aa 47 - 125. | Glyoxalase I; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.609 |
| ydhL | nemA | STM1438 | STM1436 | Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74720.1); Blastp hit to AAC74720.1 (125 aa), 83% identity in aa 47 - 125. | Similar to E. coli N-ethylmaleimide reductase (AAC74722.1); Blastp hit to AAC74722.1 (365 aa), 92% identity in aa 1 - 365. | 0.452 |
| ydhL | ydhF | STM1438 | STM1439 | Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74720.1); Blastp hit to AAC74720.1 (125 aa), 83% identity in aa 47 - 125. | Putative aldo/keto reductase; Similar to E. coli orf, hypothetical protein (AAC74719.1); Blastp hit to AAC74719.1 (298 aa), 89% identity in aa 1 - 298. | 0.645 |
| ydhL | ydhM | STM1438 | STM1437 | Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74720.1); Blastp hit to AAC74720.1 (125 aa), 83% identity in aa 47 - 125. | Putative TetR/AcrR family transcriptional repressor; Similar to E. coli orf, hypothetical protein (AAC74721.1); Blastp hit to AAC74721.1 (199 aa), 83% identity in aa 1 - 197. | 0.554 |
| ydhM | gloA | STM1437 | STM1435 | Putative TetR/AcrR family transcriptional repressor; Similar to E. coli orf, hypothetical protein (AAC74721.1); Blastp hit to AAC74721.1 (199 aa), 83% identity in aa 1 - 197. | Glyoxalase I; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.625 |
| ydhM | nemA | STM1437 | STM1436 | Putative TetR/AcrR family transcriptional repressor; Similar to E. coli orf, hypothetical protein (AAC74721.1); Blastp hit to AAC74721.1 (199 aa), 83% identity in aa 1 - 197. | Similar to E. coli N-ethylmaleimide reductase (AAC74722.1); Blastp hit to AAC74722.1 (365 aa), 92% identity in aa 1 - 365. | 0.795 |
| ydhM | ybjZ | STM1437 | STM0942 | Putative TetR/AcrR family transcriptional repressor; Similar to E. coli orf, hypothetical protein (AAC74721.1); Blastp hit to AAC74721.1 (199 aa), 83% identity in aa 1 - 197. | Putative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.461 |
| ydhM | ydcI | STM1437 | STM1625 | Putative TetR/AcrR family transcriptional repressor; Similar to E. coli orf, hypothetical protein (AAC74721.1); Blastp hit to AAC74721.1 (199 aa), 83% identity in aa 1 - 197. | Similar to E. coli putative transcriptional regulator LYSR-type (AAC74504.1); Blastp hit to AAC74504.1 (354 aa), 83% identity in aa 48 - 353; Belongs to the LysR transcriptional regulatory family. | 0.586 |