Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ydhLPutative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74720.1); Blastp hit to AAC74720.1 (125 aa), 83% identity in aa 47 - 125. (79 aa)    
Predicted Functional Partners:
yfaE
Putative ferredoxin; Similar to E. coli orf, hypothetical protein (AAC75296.1); Blastp hit to AAC75296.1 (84 aa), 96% identity in aa 1 - 84.
  
   
 0.737
yafS
Putative SAM-dependent methyltransferase; Similar to E. coli orf, hypothetical protein (AAC73318.1); Blastp hit to AAC73318.1 (246 aa), 86% identity in aa 7 - 244.
      
 0.726
nrdB
Ribonucleoside-diphosphate reductase 1, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis; Belongs to the ribonucleoside diphosphate reductase small chain family.
  
     0.700
ycaR
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74003.1); Blastp hit to AAC74003.1 (60 aa), 93% identity in aa 1 - 60; Belongs to the UPF0434 family.
  
   
 0.689
nrdA
Ribonucleoside diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide; Belongs to the ribonucleoside diphosphate reductase large chain family.
  
     0.685
yqhA
Putative membrane-associated protein; Similar to E. coli orf, hypothetical protein (AAC76038.1); Blastp hit to AAC76038.1 (164 aa), 94% identity in aa 1 - 164.
      
 0.679
yqjC
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76132.1); Blastp hit to AAC76132.1 (127 aa), 84% identity in aa 6 - 127.
  
     0.676
citG
Putative modifier of citrate lyase protein; Similar to E. coli orf, hypothetical protein (AAC73714.1); Blastp hit to AAC73714.1 (292 aa), 77% identity in aa 1 - 292.
      
 0.674
ydhF
Putative aldo/keto reductase; Similar to E. coli orf, hypothetical protein (AAC74719.1); Blastp hit to AAC74719.1 (298 aa), 89% identity in aa 1 - 298.
       0.645
syd
Interacts with secY; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.
  
     0.614
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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