node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
STM0355 | copA | STM0355 | STM0498 | Putative copper chaperone. | Putative copper-transporting ATPase; [Copper-exporting P-type ATPase]: Involved in Cu(+) export (By similarity). Essential for copper tolerance under both aerobic and anaerobic conditions. | 0.786 |
STM0355 | sodC-2 | STM0355 | STM1440 | Putative copper chaperone. | Copper/zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. | 0.753 |
ahpC | btuE | STM0608 | STM1341 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Vitamin B12 transport protein; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. | 0.420 |
ahpC | katE | STM0608 | STM1318 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | 0.963 |
ahpC | katG | STM0608 | STM4106 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Catalase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.934 |
ahpC | oxyR | STM0608 | STM4125 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Regulatory protein sensor for oxidative stress; Regulates intracellular hydrogen peroxide (LysR family); similar to E. coli activator, hydrogen peroxide-inducible genes (AAC76943.1); Blastp hit to AAC76943.1 (305 aa), 95% identity in aa 1 - 305; Belongs to the LysR transcriptional regulatory family. | 0.898 |
ahpC | sodA | STM0608 | STM4055 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family. | 0.936 |
ahpC | sodB | STM0608 | STM1431 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Iron superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family. | 0.937 |
ahpC | sodC-2 | STM0608 | STM1440 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Copper/zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. | 0.909 |
ahpC | soxR | STM0608 | STM4266 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Redox-sensing transcriptional activator SoxR; Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron- sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress (By similarity). | 0.695 |
btuE | ahpC | STM1341 | STM0608 | Vitamin B12 transport protein; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.420 |
btuE | katE | STM1341 | STM1318 | Vitamin B12 transport protein; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | 0.901 |
btuE | katG | STM1341 | STM4106 | Vitamin B12 transport protein; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. | Catalase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.828 |
btuE | sodA | STM1341 | STM4055 | Vitamin B12 transport protein; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. | Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family. | 0.735 |
btuE | sodB | STM1341 | STM1431 | Vitamin B12 transport protein; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. | Iron superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family. | 0.734 |
btuE | sodC-2 | STM1341 | STM1440 | Vitamin B12 transport protein; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. | Copper/zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. | 0.760 |
copA | STM0355 | STM0498 | STM0355 | Putative copper-transporting ATPase; [Copper-exporting P-type ATPase]: Involved in Cu(+) export (By similarity). Essential for copper tolerance under both aerobic and anaerobic conditions. | Putative copper chaperone. | 0.786 |
copA | sodC-2 | STM0498 | STM1440 | Putative copper-transporting ATPase; [Copper-exporting P-type ATPase]: Involved in Cu(+) export (By similarity). Essential for copper tolerance under both aerobic and anaerobic conditions. | Copper/zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. | 0.936 |
katE | ahpC | STM1318 | STM0608 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.963 |
katE | btuE | STM1318 | STM1341 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | Vitamin B12 transport protein; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. | 0.901 |