Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ydgKPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74698.1); Blastp hit to AAC74698.1 (154 aa), 82% identity in aa 9 - 154. (146 aa)    
Predicted Functional Partners:
yaiU
Flagellar protein; Similar to 3rd module of ATP-binding components of transporters; similar to E. coli putative flagellin structural protein (AAC73477.1); Blastp hit to AAC73477.1 (467 aa), 91% identity in aa 1 - 467.
      
 0.895
yhjD
Putative tRNA-processing ribonuclease; Similar to E. coli orf, hypothetical protein (AAC76547.1); Blastp hit to AAC76547.1 (337 aa), 85% identity in aa 1 - 336.
      
 0.858
yeiH
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75219.1); Blastp hit to AAC75219.1 (349 aa), 88% identity in aa 1 - 349.
      
 0.852
apeE
Outer membrane N-acetyl phenylalanine beta-naphthyl ester-cleaving esterase; Outer membrane esterase (gi|2896133).
      
 0.851
ydgT
Putative cytoplasmic protein; Binds to H-NS and modified the range of genes it silences; H- NS alonge silences core gene while the H-NS-Hha complex (and presumably also H-NS-YdgT) silences genes acquired by horizontal gene transfer. Plays a role silencing virulence factors in the absence of factors that induce pathogenicity (By similarity). The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC (By similarity); Belongs to the Hha/YmoA/Cnu family.
  
    0.823
rsxA
Putative inner membrane oxidoreductase protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR.
  
    0.817
ydgM
Putative alternative beta subunit of Na+-transporting NADH:ubiquinone oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
  
    0.788
yddG
Putative permease; Similar to E. coli orf, hypothetical protein (AAD13437.1); Blastp hit to AAD13437.1 (293 aa), 85% identity in aa 20 - 292.
      
 0.747
ssaD
Secretion system apparatus protein; SpiB (gi|1498308).
   
 
 0.720
sthB
Similar to E. coli putative outer membrane protein, export function (AAC73634.1); Blastp hit to AAC73634.1 (867 aa), 38% identity in aa 35 - 862.
      
 0.670
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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