| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| nth | rsxA | STM1453 | STM1459 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Putative inner membrane oxidoreductase protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. | 0.805 |
| nth | rsxC | STM1453 | STM1457 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Putative respiratory-chain NADH dehydrogenase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | 0.811 |
| nth | ydgK | STM1453 | STM1460 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74698.1); Blastp hit to AAC74698.1 (154 aa), 82% identity in aa 9 - 154. | 0.584 |
| nth | ydgM | STM1453 | STM1458 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Putative alternative beta subunit of Na+-transporting NADH:ubiquinone oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. | 0.865 |
| nth | ydgO | STM1453 | STM1456 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Putative oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the NqrB/RnfD family. | 0.880 |
| nth | ydgP | STM1453 | STM1455 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Putative Na+-transporting NADH:ubiquinone oxidoreductase gamma subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the RnfG family. | 0.973 |
| nth | ydgQ | STM1453 | STM1454 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Putative membrane NADH-quinone reductase protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. | 0.992 |
| nth | ydgT | STM1453 | STM1461 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Putative cytoplasmic protein; Binds to H-NS and modified the range of genes it silences; H- NS alonge silences core gene while the H-NS-Hha complex (and presumably also H-NS-YdgT) silences genes acquired by horizontal gene transfer. Plays a role silencing virulence factors in the absence of factors that induce pathogenicity (By similarity). The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC (By similarity); Belongs to the Hha/YmoA/Cnu family. | 0.434 |
| rsxA | nth | STM1459 | STM1453 | Putative inner membrane oxidoreductase protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.805 |
| rsxA | rsxC | STM1459 | STM1457 | Putative inner membrane oxidoreductase protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. | Putative respiratory-chain NADH dehydrogenase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | 0.994 |
| rsxA | ydgK | STM1459 | STM1460 | Putative inner membrane oxidoreductase protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74698.1); Blastp hit to AAC74698.1 (154 aa), 82% identity in aa 9 - 154. | 0.788 |
| rsxA | ydgM | STM1459 | STM1458 | Putative inner membrane oxidoreductase protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. | Putative alternative beta subunit of Na+-transporting NADH:ubiquinone oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. | 0.999 |
| rsxA | ydgO | STM1459 | STM1456 | Putative inner membrane oxidoreductase protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. | Putative oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the NqrB/RnfD family. | 0.990 |
| rsxA | ydgP | STM1459 | STM1455 | Putative inner membrane oxidoreductase protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. | Putative Na+-transporting NADH:ubiquinone oxidoreductase gamma subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the RnfG family. | 0.988 |
| rsxA | ydgQ | STM1459 | STM1454 | Putative inner membrane oxidoreductase protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. | Putative membrane NADH-quinone reductase protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. | 0.977 |
| rsxA | ydgT | STM1459 | STM1461 | Putative inner membrane oxidoreductase protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. | Putative cytoplasmic protein; Binds to H-NS and modified the range of genes it silences; H- NS alonge silences core gene while the H-NS-Hha complex (and presumably also H-NS-YdgT) silences genes acquired by horizontal gene transfer. Plays a role silencing virulence factors in the absence of factors that induce pathogenicity (By similarity). The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC (By similarity); Belongs to the Hha/YmoA/Cnu family. | 0.469 |
| rsxC | nth | STM1457 | STM1453 | Putative respiratory-chain NADH dehydrogenase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.811 |
| rsxC | rsxA | STM1457 | STM1459 | Putative respiratory-chain NADH dehydrogenase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | Putative inner membrane oxidoreductase protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR. | 0.994 |
| rsxC | ydgK | STM1457 | STM1460 | Putative respiratory-chain NADH dehydrogenase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74698.1); Blastp hit to AAC74698.1 (154 aa), 82% identity in aa 9 - 154. | 0.626 |
| rsxC | ydgM | STM1457 | STM1458 | Putative respiratory-chain NADH dehydrogenase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | Putative alternative beta subunit of Na+-transporting NADH:ubiquinone oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. | 0.996 |
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