STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydgFPutative membrane transporter of cations and cationic drugs; Catalyzes the excretion of spermidine. (120 aa)    
Predicted Functional Partners:
ydgE
Putative membrane transporter of cations and cationic drugs; Catalyzes the excretion of spermidine.
 
  
 0.999
sugE
Putative DMT superfamily transport protein; Guanidinium ion exporter. Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons. Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Gdx/SugE subfamily.
 
   
 0.936
STM1653
Putative membrane transporter of cations; Similar to E. coli methylviologen resistance (AAC73644.1); Blastp hit to AAC73644.1 (110 aa), 59% identity in aa 5 - 110.
 
  
 0.779
yhiI
Similar to E. coli putative membrane protein (AAC76512.1); Blastp hit to AAC76512.1 (355 aa), 87% identity in aa 1 - 355.
   
  
 0.728
mdfA
Multidrug translocase; Similar to E. coli proton motive force efflux pump (AAC73929.1); Blastp hit to AAC73929.1 (410 aa), 90% identity in aa 1 - 406.
  
   
 0.676
yceE
Similar to E. coli putative transport protein (AAC74137.1); Blastp hit to AAC74137.1 (408 aa), 27% identity in aa 1 - 404.
      
 0.659
ybjY
Similar to E. coli putative membrane protein (AAC73965.1); Blastp hit to AAC73965.1 (380 aa), 83% identity in aa 12 - 378; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.561
yihE
Putative homoserine kinase type II; A protein kinase that (auto)phosphorylates on Ser and Thr residues, probably involved in the extracytoplasmic stress response. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species (By similarity).
   
  
 0.557
emrA
Similar to E. coli multidrug resistance secretion protein (AAC75732.1); Blastp hit to AAC75732.1 (390 aa), 89% identity in aa 1 - 390.
   
  
 0.541
yqgB
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75976.1); Blastp hit to AAC75976.1 (48 aa), 73% identity in aa 6 - 46.
      
 0.541
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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