Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
asrAcid shock protein; Required for growth and/or survival at acidic conditions. (94 aa)    
Predicted Functional Partners:
yjbA
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77000.1); Blastp hit to AAC77000.1 (136 aa), 87% identity in aa 1 - 136; Belongs to the PsiE family.
      
 0.719
yibT
Putative cytoplasmic protein.
      
 0.676
rstA
Similar to E. coli response transcriptional regulatory protein (RstB sensor) (AAC74680.1); Blastp hit to AAC74680.1 (242 aa), 84% identity in aa 4 - 242.
     
 0.663
hdeB
Putative periplasmic transport protein; Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins. Belongs to the HdeB family.
   
  
 0.663
yhcG
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76252.1); Blastp hit to AAC76252.1 (375 aa), 55% identity in aa 115 - 164.
      
 0.649
asrB
Anaerobic sulfide reductase; This enzyme catalyzes the hydrogen sulfide production from sulfite. It is strictly anaerobic. It is regulated by electron acceptors rather than by cysteine.
      
 0.580
rmf
Ribosome modulation factor (involved in dimerization of 70S ribosomes); During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes). May form immature 90S particles, which are converted to mature 100S ribosomes by the hibernation promoting factor Hpf.
   
  
 0.572
rstB
Sensory histidine kinase in two-component regulatory system with RstA; Similar to E. coli sensor histidine protein kinase (RstA regulator) (AAC74681.1); Blastp hit to AAC74681.1 (433 aa), 82% identity in aa 1 - 433.
  
  
 0.550
ytfK
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77174.1); Blastp hit to AAC77174.1 (81 aa), 90% identity in aa 1 - 81.
      
 0.544
eda
Multifunctional; similar to E. coli 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase (AAC74920.1); Blastp hit to AAC74920.1 (213 aa), 97% identity in aa 1 - 212; oxaloacetate decarboxylase.
   
  
 0.541
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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