Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rspAPutative dehydratase; Similar to E. coli starvation sensing protein (AAC74653.1); Blastp hit to AAC74653.1 (404 aa), 94% identity in aa 1 - 404. (404 aa)    
Predicted Functional Partners:
ydfI
Putative mannitol dehydrogenase; Similar to E. coli putative oxidoreductase (AAC74615.1); Blastp hit to AAC74615.1 (486 aa), 81% identity in aa 1 - 484; Belongs to the mannitol dehydrogenase family.
 
 
 0.991
STM3136
Similar to E. coli D-mannonate oxidoreductase (AAC77279.1); Blastp hit to AAC77279.1 (486 aa), 79% identity in aa 4 - 486; Belongs to the mannitol dehydrogenase family.
 
  
 0.934
kduD
Similar to E. coli 2-deoxy-D-gluconate 3-dehydrogenase (AAC75881.1); Blastp hit to AAC75881.1 (253 aa), 93% identity in aa 1 - 253; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
  0.913
uxuA
Putative mannonate hydrolase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
    
 0.908
STM0649
Putative hydrolase N-terminus; Similar to E. coli altronate hydrolase (AAC76126.1); Blastp hit to AAC76126.1 (495 aa), 38% identity in aa 4 - 82.
    
 0.903
STM0650
Similar to E. coli putative hydrolase (AAC76162.1); Blastp hit to AAC76162.1 (523 aa), 35% identity in aa 167 - 521, 32% identity in aa 119 - 223.
  
 
 0.903
rspB
Putative dehydrogenase; Similar to E. coli starvation sensing protein (AAC74652.1); Blastp hit to AAC74652.1 (339 aa), 75% identity in aa 1 - 339.
  
  
 0.886
kdgK
Similar to E. coli ketodeoxygluconokinase (AAC76551.1); Blastp hit to AAC76551.1 (382 aa), 92% identity in aa 74 - 381.
 
  
 0.868
STM2755
Similar to E. coli probable hexulose-6-phosphate synthase (AAC77153.1); Blastp hit to AAC77153.1 (216 aa), 33% identity in aa 6 - 213.
   
 
  0.802
gnd
Gluconate-6-phosphate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
     
  0.800
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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