Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ydfZPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74614.1); Blastp hit to AAC74614.1 (67 aa), 79% identity in aa 1 - 67. (67 aa)    
Predicted Functional Partners:
hpaG
4-hydroxyphenylacetate catabolism protein; Similar to E. coli putative isomerase (AAC74264.1); Blastp hit to AAC74264.1 (219 aa), 38% identity in aa 22 - 219, 29% identity in aa 35 - 211.
      
 0.726
hpaR
4-hydroxyphenylacetate catabolism protein.
      
 0.717
yqfA
Similar to E. coli putative oxidoreductase (AAC75937.1); Blastp hit to AAC75937.1 (219 aa), 91% identity in aa 1 - 219.
      
 0.515
ydfH
Putative gntR family regulatory protein; Similar to E. coli orf, hypothetical protein (AAC74613.1); Blastp hit to AAC74613.1 (228 aa), 86% identity in aa 1 - 228.
       0.465
yfdZ
Similar to E. coli putative aminotransferase (AAC75438.1); Blastp hit to AAC75438.1 (412 aa), 95% identity in aa 1 - 412.
      
 0.451
yijC
Putative TetR/AcrR family transcriptional repressor; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
      
 0.400
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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