Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ydeJPutative competence-damaged protein; Similar to E. coli orf, hypothetical protein (AAC74610.1); Blastp hit to AAC74610.1 (172 aa), 61% identity in aa 1 - 171; Belongs to the CinA family. (175 aa)    
Predicted Functional Partners:
STM2293
Putative nucleotide-utilizing enzyme related to molybdopterin-biosynthesis; Similar to E. coli orf, hypothetical protein (AAC75309.1); Blastp hit to AAC75309.1 (400 aa), 88% identity in aa 1 - 397; Belongs to the CinA family.
 
   
 0.915
sapB
ABC superfamily peptide transport protein; Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides.
      
 0.720
STM3251
Putative ribokinase family sugar kinase; Similar to E. coli ribokinase (AAC76775.1); Blastp hit to AAC76775.1 (309 aa), 23% identity in aa 6 - 308.
      
 0.719
sapC
ABC superfamily peptide transport protein; Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
   
  
 0.653
pspE
Similar to E. coli phage shock protein (AAC74390.1); Blastp hit to AAC74390.1 (104 aa), 66% identity in aa 1 - 103.
      
 0.643
rbfA
Ribosome-binding factor; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
     
 0.572
nadD
Putative nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
  
 0.501
sapA
ABC superfamily peptide transport protein; Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides. Belongs to the bacterial solute-binding protein 5 family.
  
  
 0.495
ffh
4.5S-RNP protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to the [...]
 
   
 0.483
hisI
phosphoribosyl-AMP cyclohydrolase; Bifunctional; histidine biosynthesis bifunctional protein HISIE [includes:phosphoribosyl-amp cyclohydrolase ]. (SW:HIS2_SALTY); phosphoribosyl-ATP pyrophosphatase; In the C-terminal section; belongs to the PRA-PH family.
     
 0.477
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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