node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
abrB | marC | STM0729 | STM1521 | Similar to E. coli putative transport protein (AAC73809.1); Blastp hit to AAC73809.1 (363 aa), 80% identity in aa 16 - 361. | Putative MarC Transporter; Multiple antibiotic resistance protein MARC. (SW:MARC_SALTY). | 0.450 |
acrA | acrR | STM0476 | STM0477 | Similar to E. coli acridine efflux pump (AAC73565.1); Blastp hit to AAC73565.1 (397 aa), 91% identity in aa 1 - 397; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Similar to E. coli acrAB operon repressor (AAC73566.1); Blastp hit to AAC73566.1 (215 aa), 87% identity in aa 1 - 214. | 0.971 |
acrA | marA | STM0476 | STM1519 | Similar to E. coli acridine efflux pump (AAC73565.1); Blastp hit to AAC73565.1 (397 aa), 91% identity in aa 1 - 397; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | AraC/XylS family transcriptional activator of defense systems; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. | 0.939 |
acrA | marC | STM0476 | STM1521 | Similar to E. coli acridine efflux pump (AAC73565.1); Blastp hit to AAC73565.1 (397 aa), 91% identity in aa 1 - 397; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Putative MarC Transporter; Multiple antibiotic resistance protein MARC. (SW:MARC_SALTY). | 0.521 |
acrA | marR | STM0476 | STM1520 | Similar to E. coli acridine efflux pump (AAC73565.1); Blastp hit to AAC73565.1 (397 aa), 91% identity in aa 1 - 397; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Transcriptional repressor of marRAB operon; Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site. | 0.897 |
acrA | soxR | STM0476 | STM4266 | Similar to E. coli acridine efflux pump (AAC73565.1); Blastp hit to AAC73565.1 (397 aa), 91% identity in aa 1 - 397; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Redox-sensing transcriptional activator SoxR; Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron- sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress (By similarity). | 0.719 |
acrE | marC | STM3390 | STM1521 | Similar to E. coli transmembrane protein affects septum formation and cell membrane permeability (AAC76297.1); Blastp hit to AAC76297.1 (385 aa), 88% identity in aa 1 - 380; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Putative MarC Transporter; Multiple antibiotic resistance protein MARC. (SW:MARC_SALTY). | 0.859 |
acrE | soxR | STM3390 | STM4266 | Similar to E. coli transmembrane protein affects septum formation and cell membrane permeability (AAC76297.1); Blastp hit to AAC76297.1 (385 aa), 88% identity in aa 1 - 380; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Redox-sensing transcriptional activator SoxR; Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron- sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress (By similarity). | 0.425 |
acrR | acrA | STM0477 | STM0476 | Similar to E. coli acrAB operon repressor (AAC73566.1); Blastp hit to AAC73566.1 (215 aa), 87% identity in aa 1 - 214. | Similar to E. coli acridine efflux pump (AAC73565.1); Blastp hit to AAC73565.1 (397 aa), 91% identity in aa 1 - 397; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.971 |
acrR | marA | STM0477 | STM1519 | Similar to E. coli acrAB operon repressor (AAC73566.1); Blastp hit to AAC73566.1 (215 aa), 87% identity in aa 1 - 214. | AraC/XylS family transcriptional activator of defense systems; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. | 0.956 |
acrR | marC | STM0477 | STM1521 | Similar to E. coli acrAB operon repressor (AAC73566.1); Blastp hit to AAC73566.1 (215 aa), 87% identity in aa 1 - 214. | Putative MarC Transporter; Multiple antibiotic resistance protein MARC. (SW:MARC_SALTY). | 0.700 |
acrR | marR | STM0477 | STM1520 | Similar to E. coli acrAB operon repressor (AAC73566.1); Blastp hit to AAC73566.1 (215 aa), 87% identity in aa 1 - 214. | Transcriptional repressor of marRAB operon; Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site. | 0.939 |
acrR | soxR | STM0477 | STM4266 | Similar to E. coli acrAB operon repressor (AAC73566.1); Blastp hit to AAC73566.1 (215 aa), 87% identity in aa 1 - 214. | Redox-sensing transcriptional activator SoxR; Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron- sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress (By similarity). | 0.893 |
copR | marC | STM1096 | STM1521 | Copper resistance transcriptional regulatory protein; Pathogenicity island encoded protein: SPI5; similar to E. coli putative 2-component transcriptional regulator (AAC75035.1); Blastp hit to AAC75035.1 (239 aa), 74% identity in aa 6 - 236. | Putative MarC Transporter; Multiple antibiotic resistance protein MARC. (SW:MARC_SALTY). | 0.456 |
dapD | marC | STM0213 | STM1521 | Similar to E. coli 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase (AAC73277.1); Blastp hit to AAC73277.1 (274 aa), 97% identity in aa 1 - 274; Belongs to the transferase hexapeptide repeat family. | Putative MarC Transporter; Multiple antibiotic resistance protein MARC. (SW:MARC_SALTY). | 0.619 |
marA | acrA | STM1519 | STM0476 | AraC/XylS family transcriptional activator of defense systems; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. | Similar to E. coli acridine efflux pump (AAC73565.1); Blastp hit to AAC73565.1 (397 aa), 91% identity in aa 1 - 397; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.939 |
marA | acrR | STM1519 | STM0477 | AraC/XylS family transcriptional activator of defense systems; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. | Similar to E. coli acrAB operon repressor (AAC73566.1); Blastp hit to AAC73566.1 (215 aa), 87% identity in aa 1 - 214. | 0.956 |
marA | marB | STM1519 | STM1518 | AraC/XylS family transcriptional activator of defense systems; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. | Multiple antibiotic resistance protein MARB. (SW:MARB_SALTY). | 0.926 |
marA | marC | STM1519 | STM1521 | AraC/XylS family transcriptional activator of defense systems; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. | Putative MarC Transporter; Multiple antibiotic resistance protein MARC. (SW:MARC_SALTY). | 0.752 |
marA | marR | STM1519 | STM1520 | AraC/XylS family transcriptional activator of defense systems; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF. | Transcriptional repressor of marRAB operon; Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site. | 0.998 |