Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
STM1542Putative zinc-binding dehydrogenase; Similar to E. coli starvation sensing protein (AAC74652.1); Blastp hit to AAC74652.1 (339 aa), 32% identity in aa 1 - 337. (341 aa)    
Predicted Functional Partners:
STM1543
Similar to E. coli putative transport protein (AAC76161.1); Blastp hit to AAC76161.1 (444 aa), 32% identity in aa 17 - 433, 23% identity in aa 108 - 270.
  
    0.869
adhE
Similar to E. coli CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; pyruvate-formate-lyase deactivase (AAC74323.1); Blastp hit to AAC74323.1 (891 aa), 97% identity in aa 1 - 891; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.581
pqaA
PhoPQ-regulated protein.
  
    0.543
eutE
Putative aldehyde oxidoreductase in ethanolamine utilization; May act as an acetaldehyde dehydrogenase that converts acetaldehyde into acetyl-CoA.
    
  0.522
nifJ
Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174.
     
 0.514
STM2405
Putative thiamine pyrophosphate enzymes; Similar to E. coli acetolactate synthase III, valine sensitive, large subunit (AAC73188.1); Blastp hit to AAC73188.1 (604 aa), 24% identity in aa 37 - 505.
     
 0.511
pduC
Propanediol utilization dehydratase, large subunit; Part of the PduCDE complex that catalyzes the dehydration of 1,2-propanediol to propionaldehyde. Is required for S.typhimurium growth on 1,2-propanediol as the sole carbon and energy source.
     
 0.500
pduD
Propanediol utilization dehydratase, medium subunit; Part of the PduCDE complex that catalyzes the dehydration of 1,2-propanediol to propionaldehyde. Is required for S.typhimurium growth on 1,2-propanediol as the sole carbon and energy source.
     
  0.500
pduE
Propanediol utilization dehydratase, small subunit; Part of the PduCDE complex that catalyzes the dehydration of 1,2-propanediol to propionaldehyde. Is required for S.typhimurium growth on 1,2-propanediol as the sole carbon and energy source; Belongs to the diol/glycerol dehydratase small subunit family.
     
  0.500
eutC
Ethanolamine ammonia-lyase, light chain; Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.
     
  0.500
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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