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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hdeBPutative periplasmic transport protein; Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins. Belongs to the HdeB family. (109 aa)    
Predicted Functional Partners:
ybgS
Similar to E. coli putative homeobox protein (AAC73840.1); Blastp hit to AAC73840.1 (126 aa), 78% identity in aa 1 - 126.
   
  
 0.835
slp
Similar to E. coli putative outer membrane protein (AAC74876.1); Blastp hit to AAC74876.1 (193 aa), 90% identity in aa 1 - 193.
   
  
 0.764
STM2359
Similar to E. coli acid sensitivity protein, putative transporter (AAC74565.1); Blastp hit to AAC74565.1 (511 aa), 25% identity in aa 15 - 479.
   
  
 0.694
asr
Acid shock protein; Required for growth and/or survival at acidic conditions.
   
  
 0.567
STM1561
Putative outer membrane or secreted lipoprotein.
  
    0.499
yjdE
Putative APC family putrescine/ornithine transport protein; Major component of the acid-resistance (AR) system allowing enteric pathogens to survive the acidic environment in the stomach. Exchanges extracellular arginine for its intracellular decarboxylation product agmatine (Agm) thereby expelling intracellular protons. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
   
  
 0.497
osmC
Putative resistance protein; Osmotically inducible; similar to E. coli osmotically inducible protein (AAC74555.1); Blastp hit to AAC74555.1 (143 aa), 92% identity in aa 1 - 143.
  
  
 0.477
mgtC
Mg2+ transport protein; Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase. Belongs to the MgtC/SapB family.
   
  
 0.472
yeaQ
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74865.1); Blastp hit to AAC74865.1 (82 aa), 95% identity in aa 1 - 82.
   
  
 0.469
cybC
Cytochrome b(562); Electron-transport protein of unknown function.
      
 0.450
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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