Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
osmCPutative resistance protein; Osmotically inducible; similar to E. coli osmotically inducible protein (AAC74555.1); Blastp hit to AAC74555.1 (143 aa), 92% identity in aa 1 - 143. (143 aa)    
Predicted Functional Partners:
osmE
Similar to E. coli activator of ntrL gene (AAC74809.1); Blastp hit to AAC74809.1 (112 aa), 96% identity in aa 1 - 112.
   
  
 0.921
ygaU
Putative LysM domain protein; Similar to E. coli orf, hypothetical protein (AAC75712.1); Blastp hit to AAC75712.1 (149 aa), 93% identity in aa 1 - 149.
   
  
 0.732
dps
Stress response DNA-binding protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
  
  
 0.729
osmY
RpoS-dependent stationary phase gene; similar to E. coli hyperosmotically inducible periplasmic protein (AAC77329.1); Blastp hit to AAC77329.1 (201 aa), 89% identity in aa 1 - 201.
   
  
 0.713
yqjD
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76133.1); Blastp hit to AAC76133.1 (101 aa), 90% identity in aa 1 - 101.
  
  
 0.708
katE
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
  
 0.702
elaB
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75326.1); Blastp hit to AAC75326.1 (101 aa), 89% identity in aa 1 - 101.
   
  
 0.694
yeaG
Putative Ser protein kinase; Similar to E. coli orf, hypothetical protein (AAC74853.1); Blastp hit to AAC74853.1 (644 aa), 98% identity in aa 1 - 644.
   
  
 0.693
osmB
Osmotically inducible lipoprotein; Provides resistance to osmotic stress. May be important for stationary-phase survival (By similarity).
   
  
 0.691
rpsV
30S ribosomal subunit protein S22; Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein. Belongs to the SRA family.
   
    0.668
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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