Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
adhPAlcohol dehydrogenase; Propanol preferring; similar to E. coli alcohol dehydrogenase (AAC74551.1); Blastp hit to AAC74551.1 (346 aa), 92% identity in aa 11 - 345. (336 aa)    
Predicted Functional Partners:
adhE
Similar to E. coli CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; pyruvate-formate-lyase deactivase (AAC74323.1); Blastp hit to AAC74323.1 (891 aa), 97% identity in aa 1 - 891; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.976
eutG
Putative transport protein in ethanolamine utilization; May act on the acetaldehyde produced from the degradation of ethanolamine; Belongs to the iron-containing alcohol dehydrogenase family.
  
 0.949
STM1627
Similar to E. coli alcohol dehydrogenase class III; formaldehyde dehydrogenase, glutathione-dependent (AAC73459.1); Blastp hit to AAC73459.1 (369 aa), 80% identity in aa 1 - 369; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
0.944
STM4044
Putative iron-containing alcohol dehydrogenase; Similar to E. coli putative oxidoreductase (AAC76613.1); Blastp hit to AAC76613.1 (382 aa), 47% identity in aa 8 - 379.
  
 0.942
yjgB
Putative alcohol dehydrogenase; Similar to E. coli putative oxidoreductase (AAC77226.1); Blastp hit to AAC77226.1 (353 aa), 91% identity in aa 15 - 353.
  
 
0.929
aldB
Lactaldehyde dehydrogenase; similar to E. coli aldehyde dehydrogenase B (lactaldehyde dehydrogenase) (AAC76612.1); Blastp hit to AAC76612.1 (542 aa), 96% identity in aa 31 - 542.
  
 0.926
eutE
Putative aldehyde oxidoreductase in ethanolamine utilization; May act as an acetaldehyde dehydrogenase that converts acetaldehyde into acetyl-CoA.
   
 0.907
STM2405
Putative thiamine pyrophosphate enzymes; Similar to E. coli acetolactate synthase III, valine sensitive, large subunit (AAC73188.1); Blastp hit to AAC73188.1 (604 aa), 24% identity in aa 37 - 505.
 
 
 
 0.789
wraB
Similar to E. coli trp repressor binding protein; affects association of trp repressor and operator (AAC74089.1); Blastp hit to AAC74089.1 (198 aa), 94% identity in aa 1 - 198.
  
   0.550
sfcA
Similar to E. coli NAD-linked malate dehydrogenase (malic enzyme) (AAC74552.1); Blastp hit to AAC74552.1 (574 aa), 92% identity in aa 10 - 574; Belongs to the malic enzymes family.
  
  
 0.536
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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