STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
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[Homology]
Score
yncAPutative acyltransferase; Plays a role in the resistance against the toxic effects of L-methionine sulfoximine (MSX), a rare amino acid which inhibits glutamine synthetase (GlnA). Catalyzes the acetylation of MSX. It can also use L-methionine sulfone (MSO). Also catalyzes the acylation of free L-amino acids using an acyl-CoA as acyl donor (By similarity). (171 aa)    
Predicted Functional Partners:
ydcZ
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74529.1); Blastp hit to AAC74529.1 (149 aa), 86% identity in aa 1 - 149.
  
    0.839
aat
Leucyl, phenylalanyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
  
  
 0.741
elaA
Putative acyltransferase; Similar to E. coli orf, hypothetical protein (AAC75327.1); Blastp hit to AAC75327.1 (153 aa), 80% identity in aa 1 - 153.
  
  
 0.740
yjgM
Putative acetyltransferase; Hypothetical 18.3 Kda protein in miaE 3'region (ORF 18.3). (SW:YJGM_SALTY); Belongs to the acetyltransferase family.
     
 0.733
yiiD
Similar to E. coli putative acetyltransferase (AAD13450.1); Blastp hit to AAD13450.1 (329 aa), 93% identity in aa 1 - 329.
     
 0.725
rimJ
Similar to E. coli acetylation of N-terminal alanine of 30S ribosomal subunit protein S5 (AAC74150.1); Blastp hit to AAC74150.1 (194 aa), 95% identity in aa 1 - 194.
  
  
 0.694
yiaC
Putative acetyltransferase; Similar to E. coli orf, hypothetical protein (AAC76574.1); Blastp hit to AAC76574.1 (146 aa), 60% identity in aa 1 - 145.
  
  
 0.690
yfiQ
Putative acetyl-CoA synthetase; Acetylates and inactivates the acetyl-CoA synthase (Acs). Can also acetylate other central metabolic enzymes in response to environmental changes; In the central section; belongs to the acetate CoA ligase beta subunit family.
  
  
 0.575
yncB
Similar to E. coli putative oxidoreductase (AAC74531.1); Blastp hit to AAC74531.1 (376 aa), 85% identity in aa 28 - 375.
  
    0.525
xerD
Site-specific recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges t [...]
      
 0.476
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.