STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydcZPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74529.1); Blastp hit to AAC74529.1 (149 aa), 86% identity in aa 1 - 149. (149 aa)    
Predicted Functional Partners:
STM3549
Putative inner membrane protein.
     
  0.900
STM2912
Similar to E. coli putative transcriptional regulator LYSR-type (AAC73313.1); Blastp hit to AAC73313.1 (304 aa), 32% identity in aa 6 - 289; Belongs to the LysR transcriptional regulatory family.
      
 0.885
yncA
Putative acyltransferase; Plays a role in the resistance against the toxic effects of L-methionine sulfoximine (MSX), a rare amino acid which inhibits glutamine synthetase (GlnA). Catalyzes the acetylation of MSX. It can also use L-methionine sulfone (MSO). Also catalyzes the acylation of free L-amino acids using an acyl-CoA as acyl donor (By similarity).
  
    0.832
STM4551
Putative diguanylate cyclase/phosphodiesterase domain 1 containing protein; Similar to E. coli orf, hypothetical protein (AAC74110.1); Blastp hit to AAC74110.1 (452 aa), 41% identity in aa 274 - 444, 24% identity in aa 14 - 102.
      
 0.716
dsdA
Similar to E. coli D-serine dehydratase (deaminase) (AAC75425.1); Blastp hit to AAC75425.1 (442 aa), 89% identity in aa 1 - 442.
     
 0.686
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
    0.519
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
    0.516
yncB
Similar to E. coli putative oxidoreductase (AAC74531.1); Blastp hit to AAC74531.1 (376 aa), 85% identity in aa 28 - 375.
       0.515
pyrD
Dihydro-orotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
    0.415
yeiA
Putative dihydropyrimidine dehydrogenase; Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity).
  
    0.415
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.