Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
srfAssrAB activated gene; SrfA (gi|8347258). (439 aa)    
Predicted Functional Partners:
srfB
ssrAB activated gene; SrfB (gi|8347259).
  
 0.999
srfC
ssrAB activated gene; Predicted coiled-coil structure; SrfC (gi|8347260).
  
 0.997
cigR
Putative inner membrane protein; Pathogenicity island encoded protein: SPI3; CigR (gi|4324614).
  
   
 0.799
ecnR
Putative luxR family bacterial regulatory protein.
  
    0.747
yaiU
Flagellar protein; Similar to 3rd module of ATP-binding components of transporters; similar to E. coli putative flagellin structural protein (AAC73477.1); Blastp hit to AAC73477.1 (467 aa), 91% identity in aa 1 - 467.
  
     0.738
bcfD
Fimbrial subunit (gi|4959514).
   
  
 0.674
fliH
Flagellar biosynthesis protein; Needed for flagellar regrowth and assembly.
  
    0.674
steC
Putative inner membrane protein; Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is a kinase, which is required for SPI-2 TTSS-dependent F-actin meshwork formation in infected host cells.
      
 0.671
ycgR
Putative inner membrane protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Overexpression of this gene decreases swimming and swarming motility; those cells that are motile turn predominantly counterclockwise. The D- 118 mutant is still able to bind FliM but no longer affects motility upon overexpression. Binds 1 c-di-GMP dimer per subunit.
  
    0.599
sadA
Putative inner membrane protein; Involved in cell aggregation, biofilm formation, and adhesion to human intestinal epithelial cells; Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
   
  
 0.582
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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