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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
srfBssrAB activated gene; SrfB (gi|8347259). (993 aa)    
Predicted Functional Partners:
srfA
ssrAB activated gene; SrfA (gi|8347258).
  
 0.999
srfC
ssrAB activated gene; Predicted coiled-coil structure; SrfC (gi|8347260).
  
 0.998
STM2314
Putative chemotaxis signal transduction protein; Similar to E. coli positive regulator of CheA protein activity (AAC74957.1); Blastp hit to AAC74957.1 (167 aa), 25% identity in aa 18 - 151.
  
  
 0.778
STM3152
Similar to E. coli methyl-accepting chemotaxis protein I, serine sensor receptor (AAC77311.1); Blastp hit to AAC77311.1 (551 aa), 43% identity in aa 1 - 551.
   
  
 0.763
fliM
Flagellar biosynthesis protein; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
   
    0.692
yhhT
Putative PerM family permease; Similar to E. coli orf, hypothetical protein (AAC76499.1); Blastp hit to AAC76499.1 (376 aa), 89% identity in aa 28 - 376.
      
 0.680
ecnR
Putative luxR family bacterial regulatory protein.
  
    0.673
yaiU
Flagellar protein; Similar to 3rd module of ATP-binding components of transporters; similar to E. coli putative flagellin structural protein (AAC73477.1); Blastp hit to AAC73477.1 (467 aa), 91% identity in aa 1 - 467.
  
     0.664
fliH
Flagellar biosynthesis protein; Needed for flagellar regrowth and assembly.
  
    0.587
wcaK
Putative galactokinase; In colanic acid gene cluster; similar to E. coli putative galactokinase. (AAC75106.1); Blastp hit to AAC75106.1 (426 aa), 67% identity in aa 1 - 426.
  
     0.503
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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