STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydcRPutative gntR family regulatory protein; Similar to E. coli multi modular; putative transcriptional regulator; also putative ATP-binding component of a transport system (AAC74521.1); Blastp hit to AAC74521.1 (468 aa), 87% identity in aa 1 - 468. (474 aa)    
Predicted Functional Partners:
yicL
Putative permease; Integral membrane protein; hypothetical protein in selC 3'region. (SW:YICL_SALTY).
     
 0.721
ybeR
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73746.1); Blastp hit to AAC73746.1 (235 aa), 62% identity in aa 1 - 235.
      
 0.715
yeaM
Similar to E. coli putative ARAC-type regulatory protein (AAC74860.1); Blastp hit to AAC74860.1 (273 aa), 76% identity in aa 5 - 256.
  
  
 0.709
spoT
(p)ppGpp synthetase II; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
   
  
 0.701
yfjD
Similar to E. coli putative transport protein (AAC75662.1); Blastp hit to AAC75662.1 (227 aa), 94% identity in aa 1 - 227.
      
 0.672
hiuH
Putative periplasmic or exported protein; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
      
 0.670
ydcW
Putative aldehyde dehydrogenase; Catalyzes the oxidation 4-aminobutanal (gamma- aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4- aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
  
  
 0.543
pdgL
Periplasmic dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.
  
    0.520
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
      0.460
dfp
Flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
      
 0.459
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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